Evidence map›Paper›PMID 29882751›Full record

ArticleMolecules (Basel, Switzerland)2018

Localized In Situ Nanoemulgel Drug Delivery System of Quercetin for Periodontitis: Development and Computational Simulations.

Gururaj C Aithal, Usha Yogendra Nayak, Chetan Mehta, Reema Narayan, Pratibha Gopalkrishna, Sudharsan Pandiyan, Sanjay Garg

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 68 citations in OpenAlex.

  1. Review
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  7. Preparation,Pharmaceutical nanotechnology · 2025
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  17. Recent progress in carbon dots for anti-pathogen applications in oral cavity.Frontiers in cellular and infection microbiology · 2023
    Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Gururaj C AithalDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. gururajaithal262@gmail.com.
Usha Yogendra NayakDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. usha.nayak@manipal.edu.ORCID 0000-0002-1995-3114
Chetan MehtaDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. chetan_jd12@rediffmail.com.
Reema NarayanDepartment of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India. nsreema@gmail.com.
Pratibha GopalkrishnaDepartment of Periodontology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal 576104, India. pratibha.pk@manipal.edu.
Sudharsan PandiyanSchrödinger, Bengaluru, Karnataka 560086, India. sudharsan.pandiyan@schrodinger.com.
Sanjay GargSchool of Pharmacy and Medical Science, University of South Australia, Adelaide, SA 5000, Australia. Sanjay.Garg@unisa.edu.au.
Manipal Academy of Higher Education · INUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was aimed at formulating a bioabsorbable, controlled-release, nanoemulgel of Quercetin, a potent antimicrobial and anti-inflammatory agent for the treatment of periodontitis that could improve its solubility and bioavailability. Screening of components was carried out based on the solubility studies. Nanoemulsion containing cinnamon oil as the oil phase, tween 80 and Carbitol

Indexed as

Computer SimulationDrug Delivery SystemsGelsNanostructuresDiffusionDrug StabilityMicroscopy, Electron, TransmissionMolecular Dynamics SimulationPeriodontitisQuercetinThermodynamicsGelsQuercetinantimicrobialcomputational formulation designmolecular simulationnanoemulgelperiodontitisspontaneous emulsification

Identifiers

PMID29882751
PMCPMC6099597
OpenAlexW2806112213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.