Evidence map›Paper›PMID 29882414›Full record

ReviewFuture microbiology2018

Streptococcus sanguinis biofilm formation & interaction with oral pathogens.

Bin Zhu, Lorna C Macleod, Todd Kitten, Ping Xu

Open access · hybridAbstract readReview
In one paragraph

Review in Future microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 2 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 2 syntheses or guidelines pooled it, 233 citations in OpenAlex.

  1. Pooled it
  2. Microbial Biofilm Decontamination on Dental Implant Surfaces: A Mini Review.Frontiers in cellular and infection microbiology · 2021
    Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Susceptibility of the Oral Commensal BacteriumInternational journal of molecular sciences · 2026
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. In Vitro Antibacterial Effects ofInternational journal of dentistry · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Article

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bin ZhuPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, VA 23298, USA.
Lorna C MacleodPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, VA 23298, USA.
Todd KittenPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, VA 23298, USA.
Ping XuPhilips Institute for Oral Health Research, Virginia Commonwealth University, Richmond, VA 23298, USA.
Virginia Commonwealth University · US

Funding

Interaction of Colonizer and Pathogen In Oral BiofilmR01DE023078 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI XU, PING · 2013 to 2017
$1.9M
Regulation Of Fitness And Virulence In Oral StreptococciR01DE018138 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI XU, PING · 2008 to 2012
$1.7M
NIDCR NIH HHS R01 DE018138NIDCR NIH HHS R01 DE023078
6 · The paper itself

Abstract

Caries and periodontitis are the two most common human dental diseases and are caused by dysbiosis of oral flora. Although commensal microorganisms have been demonstrated to protect against pathogens and promote oral health, most previous studies have addressed pathogenesis rather than commensalism. Streptococcus sanguinis is a commensal bacterium that is abundant in the oral biofilm and whose presence is correlated with health. Here, we focus on the mechanism of biofilm formation in S. sanguinis and the interaction of S. sanguinis with caries- and periodontitis-associated pathogens. In addition, since S. sanguinis is well known as a cause of infective endocarditis, we discuss the relationship between S. sanguinis biofilm formation and its pathogenicity in endocarditis.

Indexed as

BiofilmsMicrobiotaAnimalsDental CariesEndocarditis, BacterialHumansStreptococcus sanguisbiofilmoral microbiotaStreptococcus sanguinis

Identifiers

PMID29882414
PMCPMC6060398
OpenAlexW2806934784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.