ArticleProteomics. Clinical applications2018
Eccrine Sweat as a Biofluid for Profiling Immune Biomarkers.
Article in Proteomics. Clinical applications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 81 citations in OpenAlex.
- No effect of tattoos on local sweat concentrations of select cytokines, cortisol, glucose, blood urea nitrogen, or lactate during exercise.Scientific reports · 2024Trial
- Tailoring NaSensors (Basel, Switzerland) · 2026Article
- Applications of Wearable Sweat Biosensors in Sports Activities with Real-World Cases.Bioengineering (Basel, Switzerland) · 2026Review
- Sweat as a diagnostic biofluid: analytical advances and future directions.Journal of pharmaceutical analysis · 2026Review
- Body Biofluids for Minimally-Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential.Advanced healthcare materials · 2026Review
- Article
- Advances in Electrochemical Nanobiosensors for Noninvasive Stress Biomarker Detection.Sensors (Basel, Switzerland) · 2025Review
- StressFit: a hybrid wearable physicochemical sensor suite for simultaneously measuring electromyogram and sweat cortisol.Scientific reports · 2024Article
- Advanced Wearable Devices for Monitoring Sweat Biochemical Markers in Athletic Performance: A Comprehensive Review.Biosensors · 2024Review
- Microparticles in Human Perspiration as an Inflammatory Response Index.Diagnostics (Basel, Switzerland) · 2024Article
- The challenges and promise of sweat sensing.Nature biotechnology · 2024Review
- Enrichment of sweat-derived extracellular vesicles of human and bacterial origin for biomarker identification.Nanotheranostics · 2024Article
- Wearing the Lab: Advances and Challenges in Skin-Interfaced Systems for Continuous Biochemical Sensing.Advances in biochemical engineering/biotechnology · 2024Review
- Field effect transistor based wearable biosensors for healthcare monitoring.Journal of nanobiotechnology · 2023Review
- Recent Advances in Skin-Interfaced Wearable Sweat Sensors: Opportunities for Equitable Personalized Medicine and Global Health Diagnostics.ACS sensors · 2023Review
- Skin-Interfaced Wearable Sweat Sensors for Precision Medicine.Chemical reviews · 2023Review
- Epidermal Wearable Biosensors for Monitoring Biomarkers of Chronic Disease in Sweat.Biosensors · 2023Review
- Proteomic profiling of sweat in patients with cystic fibrosis provides new insights into epidermal homoeostasis.Skin health and disease · 2023Article
- Wearable Microfluidic Sweat Chip for Detection of Sweat Glucose and pH in Long-Distance Running Exercise.Biosensors · 2023Article
- Wearable chemical sensors for biomarker discovery in the omics era.Nature reviews. Chemistry · 2022Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeSweat is a relatively unexplored biofluid for diagnosis and monitoring of disease states. In this study, the proteomic profiling of immune-related biomarkers from healthy individuals are presented. EXPERIMENTAL
designEccrine sweat samples are collected from 50 healthy individuals. LC-MS/MS is performed on two pools of sweat samples from five male and female participants. Individual sweat samples are analyzed by antibody isotyping microarrays (n = 49), human cytokine arrays (n = 30), and quantitative ELISAs for interleukin-1α (n = 16), epidermal growth factor (n = 6), and angiogenin (n = 7).
resultsIn sweat, 220 unique proteins are identified by shotgun analysis. Detectable antibody isotypes include IgA (100% positive; median 1230 ± 28 700 pg mL CONCLUSIONS AND CLINICAL RELEVANCE: Sweat can be used for profiling antibodies and innate immune biomarkers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.