Evidence map›Paper›PMID 29882322›Full record

Observational studyHelicobacter2018

New observations regarding Helicobacter pylori and gastric cancer in Mongolia.

Boldbaatar Gantuya, Dashdorj Bolor, Khasag Oyuntsetseg, Yansan Erdene-Ochir, Ruvjir Sanduijav, Duger Davaadorj, Tegshee Tserentogtokh, Dashdorj Azzaya, Tomohisa Uchida, Takeshi Matsuhisa and 1 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Helicobacter, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Overview ofGut and liver · 2021
    Review
  9. Article
  10. Western-TypeCancers · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Boldbaatar GantuyaDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan.
Dashdorj BolorDepartment of Endoscopy, National Cancer Center, Ulaanbaatar, Mongolia.
Khasag OyuntsetsegDepartment of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Yansan Erdene-OchirDepartment of General surgery, National Cancer Center, Ulaanbaatar, Mongolia.
Ruvjir SanduijavDepartment of Oncology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Duger DavaadorjDepartment of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Tegshee TserentogtokhDepartment of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.
Dashdorj AzzayaDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan.
Tomohisa UchidaDepartment of Molecular Pathology, Faculty of Medicine, Oita University, Yufu, Japan.
Takeshi MatsuhisaDepartment of Gastroenterology, Tama-Nagayama University Hospital of Nippon Medical School, Tama, Japan.
Yoshio YamaokaDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Yufu, Japan.ORCID http://orcid.org/0000-0002-1222-5819
Mongolian National University · MNOita University · JPBaylor College of Medicine · USNippon Medical School · JP

Funding

REGULATION OF CXC CHEMOKINE EXPRESSION BY H. PYLORIR01DK062813 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI YAMAOKA, YOSHIO · 2004 to 2013
$3.0M
NIDDK NIH HHS R01 DK062813
6 · The paper itself

Abstract

backgroundThe incidence and mortality of gastric cancer in Mongolia is among the highest in the world.

methodsThis was a case-control study in which upper gastrointestinal endoscopy, gastric histology, Helicobacter pylori testing, and risk factor questionnaires were obtained. Histologic subtypes were determined by Lauren's classification.

resultsWe enrolled 45 gastric cancer and 108 non-gastric cancer patients. Gastric cancers were located in upper part of stomach in 53.3%, main gastric body in 37.8%, and lower part of stomach in 8.9%. The majority (60%) were diffuse type, followed by intestinal type (36.7%) and indeterminate type (3.3%). H. pylori infections were CagA positive in 100% with cancer vs 81% without cancer (P = .02). The majority of CagA was non-East Asian type (95% with cancer and 94.1% without cancer). Cancer patients had typically related with excessive use of salt, hot beverages, tobacco smoking, and low ingestion of fruits.

conclusionThe characteristic topography of gastric cancer in Mongolia being in the gastric corpus differed from East Asian countries and was more similar to western countries. The risk factors for gastric cancer in Mongolia were similar to other high-risk areas (ie, H. pylori infection, excessive use of salt, tobacco smoking, and low ingestion of fruits).

Indexed as

AdultAgedCase-Control StudiesEndoscopy, GastrointestinalFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMiddle AgedMongoliaStomach Neoplasmsenvironmental risk factorsgastric cancerHelicobacter pyloriMongolia

Identifiers

PMID29882322
PMCPMC6039254
OpenAlexW2805989119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.