Evidence map›Paper›PMID 29881886›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2019

Greater magnitude tibiofemoral contact forces are associated with reduced prevalence of osteochondral pathologies 2-3 years following anterior cruciate ligament reconstruction.

David John Saxby, Adam L Bryant, Ans Van Ginckel, Yuanyuan Wang, Xinyang Wang, Luca Modenese, Pauline Gerus, Jason M Konrath, Karine Fortin, Tim V Wrigley and 7 more

Abstract read
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In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Gait Mechanics in Women of the ACL-SPORTS Randomized Control Trial: Interlimb Symmetry Improves Over Time Regardless of Treatment Group.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Trial
  3. Article
  4. Patellofemoral joint loading and early osteoarthritis after ACL reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023
    Article
  5. Males and females have different muscle activity patterns during gait after ACL injury and reconstruction.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2022
    Article
  6. Knee joint biomechanics during gait improve from 3 to 6 months after anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Sex and mechanism of injury influence knee joint loading symmetry during gait 6 months after ACLR.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Slower Walking Speed Is Related to Early Femoral Trochlear Cartilage Degradation After ACL Reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

David John SaxbyCore Group for Innovation in Health Technology, Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia. d.saxby@griffith.edu.au.
Adam L BryantCentre for Health, Exercise and Sports Medicine, University of Melbourne, Melbourne, Australia.
Ans Van GinckelCentre for Health, Exercise and Sports Medicine, University of Melbourne, Melbourne, Australia.
Yuanyuan WangDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
Xinyang WangCentre for Health, Exercise and Sports Medicine, University of Melbourne, Melbourne, Australia.
Luca ModeneseDepartment of Civil and Environmental Engineering, Imperial College London, London, UK.
Pauline GerusLaboratory of Human Motion, Education and Health, University of Nice Sophia-Antipolis, Nice, France.
Jason M KonrathCore Group for Innovation in Health Technology, Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.
Karine FortinCentre for Health, Exercise and Sports Medicine, University of Melbourne, Melbourne, Australia.
Tim V WrigleyCentre for Health, Exercise and Sports Medicine, University of Melbourne, Melbourne, Australia.
Kim L BennellCentre for Health, Exercise and Sports Medicine, University of Melbourne, Melbourne, Australia.
Flavia M CicuttiniDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia.
Christopher VertulloCore Group for Innovation in Health Technology, Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.
Julian A FellerOrthoSport Victoria, Epworth Richmond, Melbourne, Australia.
Tim WhiteheadCollege of Science, Health and Engineering, La Trobe University, Melbourne, Australia.
Price GallieCoast Orthopaedics, Gold Coast, Australia.
David G LloydCore Group for Innovation in Health Technology, Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.

Funding

National Health and Medical Research Council (AU) 1065464National Health and Medical Research Council (AU) 628850
6 · The paper itself

Abstract

purposeExternal loading of osteoarthritic and healthy knees correlates with current and future osteochondral tissue state. These relationships have not been examined following anterior cruciate ligament reconstruction. We hypothesised greater magnitude tibiofemoral contact forces were related to increased prevalence of osteochondral pathologies, and these relationships were exacerbated by concomitant meniscal injury.

methodsThis was a cross-sectional study of 100 individuals (29.7 ± 6.5 years, 78.1 ± 14.4 kg) examined 2-3 years following hamstring tendon anterior cruciate ligament reconstruction. Thirty-eight participants had concurrent meniscal pathology (30.6 ± 6.6 years, 83.3 ± 14.3 kg), which included treated and untreated meniscal injury, and 62 participants (29.8 ± 6.4 years, 74.9 ± 13.3 kg) were free of meniscal pathology. Magnetic resonance imaging of reconstructed knees was used to assess prevalence of tibiofemoral osteochondral pathologies (i.e., cartilage defects and bone marrow lesions). A calibrated electromyogram-driven neuromusculoskeletal model was used to predict medial and lateral tibiofemoral compartment contact forces from gait analysis data. Relationships between contact forces and osteochondral pathology prevalence were assessed using logistic regression models.

resultsIn patients with reconstructed knees free from meniscal pathology, greater medial contact forces were related to reduced prevalence of medial cartilage defects (odds ratio (OR) = 0.7, Wald χ

conclusionsIn patients with reconstructed knees free from meniscal pathology, increased contact forces were associated with fewer cartilage defects and bone marrow lesions in medial, but not, lateral tibiofemoral compartments. No significant relationships were found between contact forces and osteochondral pathologies in reconstructed knees with meniscal pathology for any tibiofemoral compartment. Future studies should focus on determining longitudinal effects of contact forces and changes in osteochondral pathologies. LEVEL OF EVIDENCE: IV.

Indexed as

Anterior Cruciate Ligament ReconstructionAdultAnterior Cruciate Ligament InjuriesBiomechanical PhenomenaBone MarrowCross-Sectional StudiesFemaleGaitHumansKnee InjuriesLogistic ModelsMagnetic Resonance ImagingMaleOsteonecrosisPrevalenceTibial Meniscus InjuriesAnterior cruciate ligamentBone marrow lesionsCartilageDefectsMeniscusReconstruction

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.