Evidence map›Paper›PMID 29881778›Full record

ArticleScience advances2018

Epigenome-associated phenotypic acclimatization to ocean acidification in a reef-building coral.

Yi Jin Liew, Didier Zoccola, Yong Li, Eric Tambutté, Alexander A Venn, Craig T Michell, Guoxin Cui, Eva S Deutekom, Jaap A Kaandorp, Christian R Voolstra and 4 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 198 citations in OpenAlex.

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  12. Complementary genetic and epigenetic changes facilitate rapid adaptation to multiple global change stressors.Proceedings of the National Academy of Sciences of the United States of America · 2025
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Yi Jin LiewKing Abdullah University of Science and Technology (KAUST), Red Sea Research Center, Biological and Environmental Sciences and Engineering Division, Thuwal, Saudi Arabia.ORCID 0000-0003-2553-8870
Didier ZoccolaCentre Scientifique de Monaco, Department of Marine Biology, Principality of Monaco.ORCID 0000-0002-1524-8098
Yong LiKing Abdullah University of Science and Technology (KAUST), Red Sea Research Center, Biological and Environmental Sciences and Engineering Division, Thuwal, Saudi Arabia.ORCID 0000-0003-2609-2401
Eric TambuttéCentre Scientifique de Monaco, Department of Marine Biology, Principality of Monaco.
Alexander A VennCentre Scientifique de Monaco, Department of Marine Biology, Principality of Monaco.
Craig T MichellKing Abdullah University of Science and Technology (KAUST), Red Sea Research Center, Biological and Environmental Sciences and Engineering Division, Thuwal, Saudi Arabia.
Guoxin CuiKing Abdullah University of Science and Technology (KAUST), Red Sea Research Center, Biological and Environmental Sciences and Engineering Division, Thuwal, Saudi Arabia.ORCID 0000-0003-4951-1883
Eva S DeutekomComputational Science Lab, Faculty of Science, University of Amsterdam, Amsterdam, Netherlands.
Jaap A KaandorpComputational Science Lab, Faculty of Science, University of Amsterdam, Amsterdam, Netherlands.
Christian R VoolstraKing Abdullah University of Science and Technology (KAUST), Red Sea Research Center, Biological and Environmental Sciences and Engineering Division, Thuwal, Saudi Arabia.ORCID 0000-0003-4555-3795
Sylvain ForêtResearch School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia.
Denis AllemandCentre Scientifique de Monaco, Department of Marine Biology, Principality of Monaco.ORCID 0000-0002-3089-4290
Sylvie TambuttéCentre Scientifique de Monaco, Department of Marine Biology, Principality of Monaco.
Manuel ArandaKing Abdullah University of Science and Technology (KAUST), Red Sea Research Center, Biological and Environmental Sciences and Engineering Division, Thuwal, Saudi Arabia.ORCID 0000-0001-6673-016X
King Abdullah University of Science and Technology · SAScientific Centre of Monaco · MCUniversity of Amsterdam · NLAustralian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are increasing concerns that the current rate of climate change might outpace the ability of reef-building corals to adapt to future conditions. Work on model systems has shown that environmentally induced alterations in DNA methylation can lead to phenotypic acclimatization. While DNA methylation has been reported in corals and is thought to associate with phenotypic plasticity, potential mechanisms linked to changes in whole-genome methylation have yet to be elucidated. We show that DNA methylation significantly reduces spurious transcription in the coral

Indexed as

AcclimatizationCoral ReefsEpigenesis, GeneticHydrogen-Ion ConcentrationPhenotypeAnimalsAnthozoaCarbonatesClimate ChangeDNA MethylationMitogen-Activated Protein KinasesSeawaterStress, PhysiologicalTranscription, GeneticCarbonatesMitogen-Activated Protein Kinases

Identifiers

PMID29881778
PMCPMC5990304
OpenAlexW2755635242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.