Evidence map›Paper›PMID 29881660›Full record

Article3 Biotech2018

Heliomycin and tetracinomycin D: anthraquinone derivatives with histone deacetylase inhibitory activity from marine sponge-associated

Mohamed Saleh Abdelfattah, Mohammed Ismail Youssef Elmallah, Ahmed Hassan Ibrahim Faraag, Ali Mohamed Salah Hebishy, Neama Hassan Ali

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Article
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  8. Review
  9. Frontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohamed Saleh Abdelfattah1Marine Natural Products Unit (MNPRU), Faculty of Science, Helwan University, Ain Helwan, 11795 Cairo, Egypt.ORCID 0000-0002-6416-9011
Mohammed Ismail Youssef Elmallah1Marine Natural Products Unit (MNPRU), Faculty of Science, Helwan University, Ain Helwan, 11795 Cairo, Egypt.
Ahmed Hassan Ibrahim Faraag3Botany and Microbiology Department, Faculty of Science, Helwan University, Ain Helwan, 11795 Cairo, Egypt.
Ali Mohamed Salah Hebishy1Marine Natural Products Unit (MNPRU), Faculty of Science, Helwan University, Ain Helwan, 11795 Cairo, Egypt.
Neama Hassan Ali2Chemistry Department, Faculty of Science, Helwan University, Ain Helwan, 11795 Cairo, Egypt.
Helwan University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several actinomycetes strains were isolated from different marine sponges collected from the Red Sea shore in Egypt. The efficiency of their crude extracts to inhibit histone deacetylase (HDAC) enzyme was investigated in the nuclear extract of Hela cell line. The crude extract corresponding to

Indexed as

ActinomycetesHistone deacetylaseRed SeaSponges

Identifiers

PMID29881660
PMCPMC5984605
OpenAlexW2807345056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.