ArticleJournal of intensive care2018
The lactate clearance calculated using serum lactate level 6 h after is an important prognostic predictor after extracorporeal cardiopulmonary resuscitation: a single-center retrospective observational study.
Article in Journal of intensive care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Nucleated red blood cells as early predictors of poor neurological outcome after extracorporeal cardiopulmonary resuscitation: a retrospective dual-site cohort study of early laboratory markers.Resuscitation plus · 2026Article
- Effects of Initial Lactate Levels and 24-h Lactate Clearance on Mortality in Post-Cardiac Arrest Patients: Insights from the Multicenter TIMECARD Registry.International journal of medical sciences · 2026Article
- Construction of a Mortality Prediction Model for Cardiac Arrest Patients Using Lactate Clearance Rate and Albumin-Corrected Anion Gap.Emergency medicine international · 2026Article
- Outcomes and implications of patients included vs excluded for extracorporeal cardiopulmonary resuscitation after initial activation.Resuscitation plus · 2026Article
- The absolute lactate levels versus clearance for prognostication of post-cardiotomy patients on veno-arterial ECMO.ESC heart failure · 2024Article
- Physiology-Guided Resuscitation: Monitoring and Augmenting Perfusion during Cardiopulmonary Arrest.Journal of clinical medicine · 2024Review
- Impact of clinical variables on outcomes in refractory cardiac arrest patients undergoing extracorporeal cardiopulmonary resuscitation.Frontiers in cardiovascular medicine · 2023Article
- Understanding critically ill sepsis patients with normal serum lactate levels: results from U.S. and European ICU cohorts.Scientific reports · 2021Article
- Prognosis of Hypothermic Patients Undergoing ECLS Rewarming-Do Alterations in Biochemical Parameters Matter?International journal of environmental research and public health · 2021Article
- Initial Arterial pCOMembranes · 2021Article
- The incidence and outcome of severe hyperlactatemia in critically ill patients.Internal and emergency medicine · 2021Article
- Failure of Lactate Clearance Predicts the Outcome of Critically Ill Septic Patients.Diagnostics (Basel, Switzerland) · 2020Article
- Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest in Adult Patients.Journal of the American Heart Association · 2020Review
- Prospective observational study of mechanical cardiopulmonary resuscitation, extracorporeal membrane oxygenation and early reperfusion for refractory cardiac arrest in Sydney: the 2CHEER study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2020Observational
- Correction to: The lactate clearance calculated using serum lactate level 6 h after is an important prognostic predictor after extracorporeal cardiopulmonary resuscitation: a single-center retrospective observational study.Journal of intensive care · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSerum lactate level can predict clinical outcomes in some critical cases. In the clinical setting, we noted that patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) and with poor serum lactate improvement often do not recover from cardiopulmonary arrest. Therefore, we investigated the association between lactate clearance and in-hospital mortality in cardiac arrest patients undergoing ECPR.
methodsSerum lactate levels were measured on admission and every hour after starting ECPR. Lactate clearance [(lactate at first measurement - lactate 6 h after)/lactate at first measurement × 100] was calculated 6 h after first serum lactate measurement. All patients who underwent ECPR were registered retrospectively using opt-out in our outpatient's segment.
resultIn this retrospective study, 64 cases were evaluated, and they were classified into two groups according to lactate clearance: high-clearance group, > 65%; low-clearance group, ≤ 65%. Surviving discharge rate of high-clearance group (12 cases, 63%) is significantly higher than that of low-clearance group (11 cases, 24%) (
conclusionIn our study, lactate clearance calculated through arterial blood gas analysis 6 h after ECPR was one of the most important predictors of in-hospital mortality in patients treated with ECPR after cardiac arrest.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.