Evidence map›Paper›PMID 29881616›Full record

ArticleUnited European gastroenterology journal2018

Effect of

Cesare Cremon, Simone Guglielmetti, Giorgio Gargari, Valentina Taverniti, Anna Maria Castellazzi, Chiara Valsecchi, Carlotta Tagliacarne, Walter Fiore, Massimo Bellini, Lorenzo Bertani and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 6 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 6 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Gut microbes
    Trial
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Diarrhea management: from pathophysiology to microbiota modulation.Therapeutic advances in gastroenterology · 2026
    Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 2 countries.

Cesare CremonDepartment of Medical and Surgical Sciences, Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.
Simone GuglielmettiDepartment of Food, Environmental and Nutritional Sciences, Division of Food Microbiology and Bioprocesses, University of Milan, Milan, Italy.
Giorgio GargariDepartment of Food, Environmental and Nutritional Sciences, Division of Food Microbiology and Bioprocesses, University of Milan, Milan, Italy.
Valentina TavernitiDepartment of Food, Environmental and Nutritional Sciences, Division of Food Microbiology and Bioprocesses, University of Milan, Milan, Italy.
Anna Maria CastellazziDepartment of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Chiara ValsecchiDepartment of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Carlotta TagliacarneDepartment of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.
Walter Fiore4Sofar S.p.A., Trezzano Rosa, Italy.
Massimo BelliniGastroenterology Unit, Department of Gastroenterology, University of Pisa, Pisa, Italy.
Lorenzo BertaniGastroenterology Unit, Department of Gastroenterology, University of Pisa, Pisa, Italy.
Dario GambacciniGastroenterology Unit, Department of Gastroenterology, University of Pisa, Pisa, Italy.
Michele CicalaGastroenterology Unit, University Campus Bio-Medico of Rome, Rome, Italy.
Bastianello GermanàGastroenterology Unit, S. Martino Hospital, Belluno, Italy.
Maurizio Vecchi8Gastroenterology and Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Isabella PaganoDepartment of Medical and Surgical Sciences, Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.
Maria Raffaella BarbaroDepartment of Medical and Surgical Sciences, Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.
Lara BellacosaDepartment of Medical and Surgical Sciences, Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.
Vincenzo StanghelliniDepartment of Medical and Surgical Sciences, Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.
Giovanni BarbaraDepartment of Medical and Surgical Sciences, Centre for Applied Biomedical Research, University of Bologna, Bologna, Italy.
Medica (Italy) · ITUniversity of Milan · ITUniversity of Pavia · ITUniversity of Pisa · ITIRCCS Policlinico San Donato · ITMartin University · USSofar (Italy) · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence suggests a role of intestinal microbiota-host interactions in the pathophysiology and symptoms of irritable bowel syndrome (IBS).

objectiveThe objective of this article is to assess the effects of

methodsWe conducted a multicenter, randomized, double-blind, cross-over, 18-week, placebo-controlled, pilot trial assessing the effect of

resultsForty IBS patients were enrolled from five Italian centers.

conclusionsThis pilot study shows that

Indexed as

dietary compoundsIrritable bowel syndromemicrobiotaprobiotics

Identifiers

PMID29881616
PMCPMC5987284
OpenAlexW2761380627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.