Evidence map›Paper›PMID 29881570›Full record

ArticleClinical case reports2018

Leukemic mature B-cell neoplasm observed during the treatment with romiplostim in patient with thrombocytopenia and liver cirrhosis.

Marina Osawa, Hideki Akiyama, Sunao Mae, Yuko Fujiwara, Michio Yamane

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marina OsawaDepartment of Medicine Nitobe Memorial Nakano General Hospital 4-59-16, Chuou Nakano Tokyo 164-8607 Japan.
Hideki AkiyamaDepartment of Medicine Nitobe Memorial Nakano General Hospital 4-59-16, Chuou Nakano Tokyo 164-8607 Japan.ORCID 0000-0001-5788-8555
Sunao MaeDepartment of Medicine Nitobe Memorial Nakano General Hospital 4-59-16, Chuou Nakano Tokyo 164-8607 Japan.
Yuko FujiwaraDepartment of Medicine Nitobe Memorial Nakano General Hospital 4-59-16, Chuou Nakano Tokyo 164-8607 Japan.
Michio YamaneDepartment of Medicine Nitobe Memorial Nakano General Hospital 4-59-16, Chuou Nakano Tokyo 164-8607 Japan.
Nitobe Memorial Nakano General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here a new adverse event of romiplostim which is a protein analog of thrombopoietin. Leukemic mature B-cell neoplasm was observed during the treatment of thrombocytopenia in a patient with liver cirrhosis. Their relationship was suggested clinically but the mechanism of leukemic expansion of lymphoma cells was not clarified.

Indexed as

Cirrhosismature B‐cell neoplasmromiplostim

Identifiers

PMID29881570
PMCPMC5986044
OpenAlexW2800119172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.