Evidence map›Paper›PMID 29881525›Full record

ArticleElectronic physician2018

Effect of adding dexamethasone to lidocaine on the quality of intravenous regional anesthesia for upper extremity orthopedic operations: A randomized clinical trial.

Abbas Moallemy, Hashem Jarineshin, Fereydoon Fekrat, Alireza Abdullahzadeh Baghaaei, Manuchehr Kamali, Bibi Mona Razavi, Zobeir Shaerzadeh

Open access · goldAbstract read
In one paragraph

Article in Electronic physician, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Abbas MoallemyMD, Assistant Professor of Anesthesiology, Pain Management Fellowship, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences. Bandar Abbas, Iran.
Hashem JarineshinMD, Associate Professor of Anesthesiology, Cardiac and Thoracic Anesthesia Fellowship, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences. Bandar Abbas, Iran.
Fereydoon FekratMD, Anesthesiology Specialist, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences. Bandar Abbas, Iran.
Alireza Abdullahzadeh BaghaaeiMD, Assistant Professor of Anesthesiology, Pain Management Fellowship, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences. Bandar Abbas, Iran.
Manuchehr KamaliMD, Anesthesiology Specialist, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences. Bandar Abbas, Iran.
Bibi Mona RazaviMD, Anesthesiology Resident, Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences. Bandar Abbas, Iran.
Zobeir ShaerzadehMD, Assistant Professor of Surgery, Anesthesioligy, Critical care and Pain Management Research Center, Hormozgan University of Medical Sciences. Bandar Abbas, Iran.
Hormozgan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntravenous regional anesthesia (IVRA) is an ideal technique for short surgery on the distal extremities. Different additives have been used to improve lidocaine's block quality.

objectiveThe aim of this study was to determine the effect of adding dexamethasone to lidocaine on improving the quality of IVRA.

methodsThis study is a prospective, double-blind randomized study which was done on patients with upper extremity injuries of the distal elbow in Shahid Mohammadi Hospital, Bandar Abbas from October 2014 to December 2015. A total of 110 patients aged 15 to 65 years, with ASA class I and II, with orthopedic injuries distal to the elbow, were randomly divided into two groups. The control group (L) and the intervention group (L+D) received a 40-ml solution of 3 mg/kg lidocaine, and 3 mg/kg lidocaine + 8 mg of dexamethasone respectively. The two groups were compared in terms of onset and recovery time of sensory block in each of the dermatome nerves classified as radial, ulnar, and median, vital signs, patient satisfaction, intraoperative opioid consumption, and request for the first postoperative opioid.

resultsThere was no significant difference between the two groups in terms of demographic characteristics. Mean arterial blood pressure was higher in the L + D group (100.39±14.6 mmHg) in comparison to the L group (90.50±11 mmHg) (p=0.002). Need for opioid was reported in 20 (35.7%) patients in the L + D group in comparison to 17 (31.5%) in the L group (p=0.639). The average intraoperative dose of fentanyl was 95±32.04 mcg and 88.44±18.77 mg in L + D and L groups respectively and there was no significant difference between the two groups in this respect (p=0.479). In addition, the average dose of pethidine administered in the recovery room for L + D group (19.34±15.22) mg was significantly higher than in the L group (9.44±12.26 mg) (p=0.001).

conclusionsAdding 8 mg dexamethasone to lidocaine has no effect on IVRA solution in upper extremity orthopedic operations and also increases postoperative opioid consumption.

trial registrationThe trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the Irct ID: IRCT2016052928158N1.

fundingThe authors received financial support from Hormozgan University of Medical Sciences.

Indexed as

AdditiveDexamethasoneLidocaineUpper extremity

Identifiers

PMID29881525
PMCPMC5984017
OpenAlexW2801171422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.