Evidence map›Paper›PMID 29881422›Full record

ArticleIranian journal of pharmaceutical research : IJPR2018

Wedelolactone from Vietnamese

Trinh Tat Cuong, Giang Huy Diem, Tran Trung Doan, Nguyen Quang Huy, Nguyen Phuong, Hoang The Hung

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway.Oxidative medicine and cellular longevity · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Trinh Tat CuongKey Laboratory for Enzyme and Protein Technology, Hanoi University of Science, Hanoi, Vietnam.
Giang Huy DiemKey Laboratory for Enzyme and Protein Technology, Hanoi University of Science, Hanoi, Vietnam.
Tran Trung DoanKey Laboratory for Enzyme and Protein Technology, Hanoi University of Science, Hanoi, Vietnam.
Nguyen Quang HuyFaculty of Biology, Hanoi University of Science, Hanoi, Vietnam.
Nguyen PhuongNational centre for Technological progress, Hanoi, Vietnam.
Hoang The HungInstitute of scientific research in military logistics/military academy of logistic, Hanoi, Vietnam.
VNU University of Science · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wedelolactone is known to have biological activities such as anti-inflammation hepatitis, anti-hepatotoxic activity, and trypsin inhibitory effect. However, up to date, there has not been any deep study on the role of wedelolactone for zymosan-induced signaling pathways in the process of regulating the excessive inflammatory responses in host. Here, we demonstrated that wedelolactone plays an essential role for regulation of zymosan-induced inflammatory responses in murine bone marrow-derived macrophages (BMDMs). The zymosan-mediated secretion of tumor necrosis factor-α (TNF)-α), interleukin (IL)-6), and IL12p40 but not IL-10 in BMDMs was significantly inhibited by pre-treatment with wedelolactone (30 µg/mL,

Indexed as

InflammationReactive oxygen speciessepsisWedelolactonezymosan

Identifiers

PMID29881422
PMCPMC5985182
OpenAlexW2788721803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.