Evidence map›Paper›PMID 29881339›Full record

ArticleFrontiers in neuroinformatics2018

New Protocol for Quantitative Analysis of Brain Cortex Electroencephalographic Activity in Patients With Psychiatric Disorders.

Grzegorz M Wojcik, Jolanta Masiak, Andrzej Kawiak, Piotr Schneider, Lukasz Kwasniewicz, Nikodem Polak, Anna Gajos-Balinska

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Grzegorz M WojcikFaculty of Mathematics, Physics and Computer Science, Institute of Computer Science-Department of Neuroinformatics, Maria Curie-Sklodowska University in Lublin, Lublin, Poland.
Jolanta MasiakNeurophysiological Independent Unit of the Department of Psychiatry, Medical University of Lublin, Lublin, Poland.
Andrzej KawiakFaculty of Mathematics, Physics and Computer Science, Institute of Computer Science-Department of Neuroinformatics, Maria Curie-Sklodowska University in Lublin, Lublin, Poland.
Piotr SchneiderFaculty of Mathematics, Physics and Computer Science, Institute of Computer Science-Department of Neuroinformatics, Maria Curie-Sklodowska University in Lublin, Lublin, Poland.
Lukasz KwasniewiczFaculty of Mathematics, Physics and Computer Science, Institute of Computer Science-Department of Neuroinformatics, Maria Curie-Sklodowska University in Lublin, Lublin, Poland.
Nikodem PolakFaculty of Mathematics, Physics and Computer Science, Institute of Computer Science-Department of Neuroinformatics, Maria Curie-Sklodowska University in Lublin, Lublin, Poland.
Anna Gajos-BalinskaFaculty of Mathematics, Physics and Computer Science, Institute of Computer Science-Department of Neuroinformatics, Maria Curie-Sklodowska University in Lublin, Lublin, Poland.
Institute of Computer Science · PLMaria Curie-Skłodowska University · PLMedical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interview is still the main and most important tool in psychiatrist's work. The neuroimaging methods such as CT or MRI are widely used in other fields of medicine, for instance neurology. However, psychiatry lacks effective quantitative methods to support of diagnosis. A novel neuroinformatic approach to help clinical patients by means of electroencephalographic technology in order to build foundations for finding neurophysiological biomarkers of psychiatric disorders is proposed. A cohort of 30 right-handed patients (21 males, 9 females) with psychiatric disorders (mainly with panic and anxiety disorder, Asperger syndrome as well as with phobic anxiety disorders, schizophrenia, bipolar affective disorder, obsessive-compulsive disorder, nonorganic hypersomnia, and moderate depressive episode) were examined using the dense array EEG amplifier in the P300 experiment. The results were compared with the control group of 30 healthy, right-handed male volunteers. The quantitative analysis of cortical activity was conducted using the sLORETA source localization algorithm. The most active Brodmann Areas were pointed out and a new quantitative observable of electrical charge flowing through the selected Brodmann Area is proposed. The precise methodology and research protocol for collecting EEG data as well as the roadmap of future investigations in this area are presented. The essential result of this study is the idea proven by the initial results of our experiments that it is possible to determine quantitatively biomarkers of particular psychiatric disorders in order to support the process of diagnosis and hopefully choose most appropriate medical treatment later.

Indexed as

biomarkerselectroencephalographyP300psychiatric disordersquantitative analysissLORETA

Identifiers

PMID29881339
PMCPMC5976787
OpenAlexW2800290631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.