Evidence map›Paper›PMID 29880794›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2018

Inadequate iron stores in early term neonates.

Ying Hua, Niko Kaciroti, Yaping Jiang, Xing Li, Guobin Xu, Blair Richards, Ming Li, Betsy Lozoff

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ying HuaPeking University First Hospital, Beijing, China.
Niko KacirotiCenter for Human Growth and Development, University of Michigan, Ann Arbor, MI, USA.
Yaping JiangPeking University First Hospital, Beijing, China.
Xing LiPeking University First Hospital, Beijing, China.
Guobin XuPeking University First Hospital, Beijing, China.
Blair RichardsCenter for Human Growth and Development, University of Michigan, Ann Arbor, MI, USA.
Ming LiPeking University First Hospital, Beijing, China. mlixu@msn.com.
Betsy LozoffCenter for Human Growth and Development, University of Michigan, Ann Arbor, MI, USA. blozoff@umich.edu.
Peking University First Hospital · CNUniversity of Michigan–Ann Arbor · USPeking University · CN

Funding

Timing, Duration and Severity of Infant Iron Deficiency: Developmental ImpactsR01HD052069 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOZOFF, BETSY · 2007 to 2011
$3.9M
NICHD NIH HHS R01 HD052069
6 · The paper itself

Abstract

objectiveTo characterize neonatal iron stores depending on gestational age (GA) at term. STUDY

designParticipants were 751 mother-newborn pairs from the placebo arm of a randomized clinical trial of prenatal iron-folate supplementation in China. We compared mean cord serum ferritin (SF) by weeks GA and, following the general linear model, assessed whether maternal iron deficiency (ID) influenced relations between GA and cord SF.

resultsControlling for covariates, cord SF increased between 37 and 41 weeks (ps < 0.05-0.01). Cord SF was lower in infants of ID vs. non-ID mothers (geometric mean 96.3 [95% CI: 91.3-101.6] µg/L vs. 115.9 [95% CI: 105.0-127.8] µg/L, effect size = 0.33 SD, p = 0.0012). There was no significant increase with GA among infants of ID mothers. For non-ID mothers, cord-blood SF increased sharply with GA until 38 5/7 weeks, after which it plateaued.

conclusionsThe findings emphasize that neonates at 37-38 weeks, although considered term, are not fully mature.

Indexed as

Gestational AgeAdultAnemia, Iron-DeficiencyChinaDietary SupplementsFemaleFerritinsFetal BloodFolic AcidHumansInfant, NewbornIronLinear ModelsMaleMaternal-Fetal ExchangePregnancyFerritinsFolic AcidIron

Identifiers

PMID29880794
PMCPMC6136963
OpenAlexW2807273066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.