Evidence map›Paper›PMID 29880750›Full record

Trial reportNutrients2018

Effects of Glutamine on Gastric Emptying of Low- and High-Nutrient Drinks in Healthy Young Subjects-Impact on Glycaemia.

Yang T Du, Diana Piscitelli, Saima Ahmad, Laurence G Trahair, Jerry R Greenfield, Dorit Samocha-Bonet, Christopher K Rayner, Michael Horowitz, Karen L Jones

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yang T DuEndocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia. yang.timothy.du@gmail.com.ORCID 0000-0002-1741-9866
Diana PiscitelliAdelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia. diana.piscitelli@adelaide.edu.au.ORCID 0000-0003-3894-8203
Saima AhmadSchool of Health Sciences, University of South Australia, Adelaide, SA 5000, Australia. saima.ahmad010@gmail.com.
Laurence G TrahairAdelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia. laurence.trahair@adelaide.edu.au.
Jerry R GreenfieldDiabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia. j.greenfield@garvan.org.au.
Dorit Samocha-BonetDiabetes and Metabolism Division, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia. d.samochabonet@garvan.org.au.ORCID 0000-0001-9422-7852
Christopher K RaynerAdelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia. chris.rayner@adelaide.edu.au.
Michael HorowitzEndocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia. michael.horowitz@adelaide.edu.au.
Karen L JonesAdelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia. karen.jones@adelaide.edu.au.
Royal Adelaide Hospital · AUUniversity of South Australia · AUGarvan Institute of Medical Research · AUNational Health and Medical Research Council · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutamine is a potent stimulus for the release of glucagon-like peptide-1, which increases postprandial insulin and slows gastric emptying (GE). We determined the effects of glutamine on GE of, and glycaemic responses to, low- and high-nutrient drinks in eight healthy males (mean age 21.6 ± 0.7 years and BMI 22.9 ± 0.7 kg/m²). Participants were studied on four occasions on which they consumed either a low-nutrient (beef soup; 18 kcal) or high-nutrient (75 g dextrose; 255 kcal) drink, each with or without 30 g of glutamine (120 kcal), in a randomised, crossover design. GE (2D ultrasound), blood glucose and plasma insulin concentrations were measured concurrently. Glutamine slowed GE (half emptying time (T50)) of both low- (45 ± 3 min vs. 26 ± 2 min,

Indexed as

Dietary SupplementsEnergy DrinksNutritive ValueAdministration, OralAge FactorsBiomarkersBlood GlucoseCross-Over StudiesDouble-Blind MethodGastric EmptyingGlutamineHealthy VolunteersHumansInsulinMaleSouth AustraliaBiomarkersBlood GlucoseGlutamineInsulingastric emptyingglucoseglutamineglycaemiainsulinpostprandial

Identifiers

PMID29880750
PMCPMC6024320
OpenAlexW2806745089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.