Evidence map›Paper›PMID 29880611›Full record

ArticleHaematologica2018

Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy.

Constance C F M J Baaten, Floor C J I Moenen, Yvonne M C Henskens, Frauke Swieringa, Rick J H Wetzels, René van Oerle, Harry F G Heijnen, Hugo Ten Cate, Graham P Holloway, Erik A M Beckers and 2 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

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  18. Frontiers in pharmacology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Constance C F M J BaatenDepartment of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, the Netherlands.
Floor C J I MoenenDepartment of Hematology, Maastricht University Medical Centre, the Netherlands.
Yvonne M C HenskensCentral Diagnostic Laboratory, Maastricht University Medical Centre, the Netherlands.
Frauke SwieringaDepartment of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, the Netherlands.
Rick J H WetzelsCentral Diagnostic Laboratory, Maastricht University Medical Centre, the Netherlands.
René van OerleCentral Diagnostic Laboratory, Maastricht University Medical Centre, the Netherlands.
Harry F G HeijnenDepartment of Cell Biology and Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, the Netherlands.
Hugo Ten CateDepartment of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, the Netherlands.
Graham P HollowayDepartment of Human Health and Nutritional Sciences, University of Guelph, Ontario, Canada.
Erik A M BeckersDepartment of Hematology, Maastricht University Medical Centre, the Netherlands.
Johan W M HeemskerkDepartment of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, the Netherlands.
Paola E J van der MeijdenDepartment of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, the Netherlands p.vandermeijden@maastrichtuniversity.nl.
Maastricht University Medical Centre · NLLeibniz Institute for Analytical Sciences - ISAS · DEMaastricht University · NLUniversity Medical Center Utrecht · NLUniversity of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe thrombocytopenia (≤50×10

Indexed as

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsApoptosisBiomarkersBlood CoagulationBlood PlateletsCalcium SignalingCase-Control StudiesFemaleHumansMaleMiddle AgedMitochondriaNeoplasmsPlatelet ActivationBiomarkers

Identifiers

PMID29880611
PMCPMC6119160
OpenAlexW2807339320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.