Evidence map›Paper›PMID 29880479›Full record

ArticleAJNR. American journal of neuroradiology2018

Improved Detection of New MS Lesions during Follow-Up Using an Automated MR Coregistration-Fusion Method.

A Galletto Pregliasco, A Collin, A Guéguen, M A Metten, J Aboab, R Deschamps, O Gout, L Duron, J C Sadik, J Savatovsky and 1 more

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  9. Utility of image fusion software in identifying shunt malfunction.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

A Galletto PregliascoFrom the Departments of Radiology (A.G.P., A.C., L.D., J.C.S., J.S., A.L.).ORCID 0000-0001-8827-4740
A CollinFrom the Departments of Radiology (A.G.P., A.C., L.D., J.C.S., J.S., A.L.).ORCID 0000-0003-4271-7889
A GuéguenNeurology (A.G., J.A., R.D., O.G.).ORCID 0000-0001-5170-5818
M A MettenClinical Research Unit (M.A.M.), Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.ORCID 0000-0002-2370-8816
J AboabNeurology (A.G., J.A., R.D., O.G.).ORCID 0000-0002-5022-4681
R DeschampsNeurology (A.G., J.A., R.D., O.G.).ORCID 0000-0001-6291-8771
O GoutNeurology (A.G., J.A., R.D., O.G.).ORCID 0000-0001-6435-0761
L DuronFrom the Departments of Radiology (A.G.P., A.C., L.D., J.C.S., J.S., A.L.).ORCID 0000-0002-4279-1176
J C SadikFrom the Departments of Radiology (A.G.P., A.C., L.D., J.C.S., J.S., A.L.).ORCID 0000-0003-1429-5631
J SavatovskyFrom the Departments of Radiology (A.G.P., A.C., L.D., J.C.S., J.S., A.L.).ORCID 0000-0002-6732-1779
A LeclerFrom the Departments of Radiology (A.G.P., A.C., L.D., J.C.S., J.S., A.L.) alecler@for.paris.ORCID 0000-0001-7869-1815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMR imaging is the key examination in the follow-up of patients with MS, by identification of new high-signal T2 brain lesions. However, identifying new lesions when scrolling through 2 follow-up MR images can be difficult and time-consuming. Our aim was to compare an automated coregistration-fusion reading approach with the standard approach by identifying new high-signal T2 brain lesions in patients with multiple sclerosis during follow-up MR imaging. MATERIALS AND

methodsThis prospective monocenter study included 94 patients (mean age, 38.9 years) treated for MS with dimethyl fumarate from January 2014 to August 2016. One senior neuroradiologist and 1 junior radiologist checked for new high-signal T2 brain lesions, independently analyzing blinded image datasets with automated coregistration-fusion or the standard scroll-through approach with a 3-week delay between the 2 readings. A consensus reading with a second senior neuroradiologist served as a criterion standard for analyses. A Poisson regression and logistic and γ regressions were used to compare the 2 methods. Intra- and interobserver agreement was assessed by the κ coefficient.

resultsThere were significantly more new high-signal T2 lesions per patient detected with the coregistration-fusion method (7 versus 4,

conclusionsOur study showed that an automated coregistration-fusion method was more sensitive for detecting new high-signal T2 lesions in patients with MS and reducing reading time. This method could help to improve follow-up care.

Indexed as

AdultBrainFemaleFollow-Up StudiesHumansImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisNeuroimagingRetrospective Studies

Identifiers

PMID29880479
PMCPMC7655423

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.