Evidence map›Paper›PMID 29880442›Full record

ArticleSeminars in arthritis and rheumatism2019

Arterial lesions in giant cell arteritis: A longitudinal study.

Tanaz A Kermani, Sehriban Diab, Antoine G Sreih, David Cuthbertson, Renée Borchin, Simon Carette, Lindsy Forbess, Curry L Koening, Carol A McAlear, Paul A Monach and 10 more

Open access · greenAbstract read
In one paragraph

Article in Seminars in arthritis and rheumatism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. ACR Appropriateness Criteria® Noncerebral Vasculitis.Journal of the American College of Radiology : JACR · 2021
    Guideline
  3. Guideline
  4. Guideline
  5. Pooled it
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Association ofArthritis & rheumatology (Hoboken, N.J.) · 2023
    Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Comparing Semiquantitative and Qualitative Methods of VascularJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Observational
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 13 institutions in 2 countries.

Tanaz A KermaniDivision of Rheumatology, University of California Los Angeles, 2020 Santa Monica Boulevard, Suite 540 Santa Monica, CA 90404. Electronic address: TKermani@mednet.ucla.edu.
Sehriban DiabDivision of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, ON, Canada.
Antoine G SreihDivision of Rheumatology, University of Pennsylvania, Philadelphia, PA.
David CuthbertsonDepartment of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL.
Renée BorchinDepartment of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL.
Simon CaretteDivision of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada.
Lindsy ForbessDivision of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA.
Curry L KoeningDivision of Rheumatology, University of Utah, Salt Lake City, UT.
Carol A McAlearDivision of Rheumatology, University of Pennsylvania, Philadelphia, PA.
Paul A MonachSection of Rheumatology, Boston University School of Medicine, Boston, MA.
Larry MorelandDivision of Rheumatology, University of Pittsburgh, Pittsburgh, PA.
Christian PagnouxDivision of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada.
Philip SeoDivision of Rheumatology, Johns Hopkins University, Baltimore, MD.
Robert F SpieraDivision of Rheumatology, Hospital for Special Surgery, New York, NY.
Kenneth J WarringtonDivision of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN.
Steven R YtterbergDivision of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN.
Carol A LangfordDepartment of Rheumatic and Immunologic Diseases, Cleveland Clinic, Lerner College of Medicine, Cleveland, OH.
Peter A MerkelDivision of Rheumatology and the Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, PA.
Nader A KhalidiDivision of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, ON, Canada.
Vasculitis Clinical Research Consortium
University of Pennsylvania · USMayo Clinic in Arizona · USMount Sinai Hospital · CASt. Joseph’s Healthcare Hamilton · CAUniversity of South Florida · USBoston University · USCedars-Sinai Medical Center · USCleveland Clinic Lerner College of Medicine · USHospital for Special Surgery · USJohns Hopkins University · USUniversity of California, Los Angeles · USUniversity of Pittsburgh · USUniversity of Utah · US

Funding

VCRC-VF FellowshipU54AR057319 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MERKEL, PETER A · 2009 to 2020
$12.5M
VASCULITIS CLINICAL RESEARCH NETWORK (VCRN): RARE DISEASEU54RR019497 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MERKEL, PETER A · 2003 to 2008
$6.1M
NCRR NIH HHS U54 RR019497NIAMS NIH HHS U54 AR057319
6 · The paper itself

Abstract

objectivesTo evaluate large-vessel (LV) abnormalities on serial imaging in patients with giant cell arteritis (GCA) and discern predictors of new lesions.

methodsClinical and imaging data from patients with GCA (including subjects diagnosed by LV imaging) enrolled in a prospective, multicenter, longitudinal study and/or a randomized clinical trial were included. New arterial lesions were defined as a lesion in a previously unaffected artery.

resultsThe study included 187 patients with GCA, 146 (78%) female, mean (±SD) age at diagnosis 68.5 ± 8.5 years; 39% diagnosed by LV imaging. At least one arterial lesion was present in 123 (66%) on the first study. The most frequently affected arteries were subclavian (42%), axillary (32%), and thoracic aorta (20%). In 106 patients (57%) with serial imaging, new arterial lesions were noted in 41 patients (39%), all of whom had a baseline abnormality, over a mean (±SD) follow-up of 4.39 (2.22) years. New abnormalities were observed in 33% patients by year 2; clinical features of active disease were present at only 50% of these cases. There were no differences in age, sex, temporal artery biopsy positivity, or disease activity in patients with or without new lesions.

conclusionsIn this cohort of patients with GCA, LV abnormalities on first imaging were common. Development of new arterial lesions occurred in patients with arterial abnormalities at first imaging, often in the absence of symptoms of active disease. Arterial imaging should be considered in all patients with GCA at diagnosis and serial imaging at least in patients with baseline abnormalities.

Indexed as

AgedAorta, ThoracicAxillary ArteryComputed Tomography AngiographyFemaleGiant Cell ArteritisHumansLongitudinal StudiesMagnetic Resonance AngiographyMaleMiddle AgedSubclavian ArteryAortic aneurysmComputed tomography angiographyDisease activityGiant cell arteritisLarge-artery stenosisMagnetic resonance angiography

Identifiers

PMID29880442
PMCPMC6226363
OpenAlexW2800737042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.