Evidence map›Paper›PMID 29880009›Full record

ArticleTrials2018

Efficacy of acupuncture on pelvic pain in patients with endometriosis: study protocol for a randomized, single-blind, multi-center, placebo-controlled trial.

Ruining Liang, Peishuang Li, Xuemei Peng, Ling Xu, Pei Fan, Jiahua Peng, Xu Zhou, Chunlin Xiao, Miao Jiang

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03125304 (Acupuncture for Pain of Endometriosis), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03125304 nacompletednot on this map

Acupuncture for Pain of Endometriosis: A Multicenter, Randomized, and Controlled Trial

TypeinterventionalSponsorState Administration of Traditional Chinese Medicine of the People's Republic of ChinaRan2017 to 2021Enrolled106ConditionsEndometriosisArmsacupuncture
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. [Holistic treatment of endometriosis].Schmerz (Berlin, Germany) · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Purinergic Signaling in Endometriosis-Associated Pain.International journal of molecular sciences · 2020
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ruining LiangInstitute of Obstetrics and Gynecology, Jiangxi University of Traditional Chinese Medicine, Nanchang, China. jack169@sina.com.
Peishuang LiDepartment of Gynecology, the Affiliated Hospital, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Xuemei PengDepartment of Traditional Chinese Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Ling XuDepartment of Obstetrics and Gynecology, the Second Affiliated Hospital, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Pei FanDepartment of Obstetrics and Gynecology, the Second Affiliated Hospital, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Jiahua PengInstitute of Obstetrics and Gynecology, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Xu ZhouEvidence-based Medical Center, School of Basic Medical Sciences, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Chunlin XiaoDepartment of Characteristic Therapy with Traditional Chinese Medicine, the Affiliated Hospital, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Miao JiangDepartment of Traditional Chinese Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Jiangxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndometriosis is a chronic gynecological disease that is characterized by the presence of endometrial tissue outside the uterine cavity. The main symptoms include dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. These symptoms impair the lives of most of the women suffering from the disease. Surgical resection of endometriotic lesions is an effective means of treating dysmenorrhea, but the risk of recurrence is high. Western medicine has limited use for treating it due to side effects and ineffectiveness. The purpose of this study is to verify the effectiveness and safety of acupuncture. METHODS/

designThis trial will be carried out in four parts. A total of 106 eligible patients with pelvic pain related to endometriosis will be randomly assigned into two groups, in a 1:1 ratio, as the treatment group or the control group. The participants assigned to the treatment group will be treated with acupuncture treatment at Guanyuan (CV4), Sanyinjiao (SP6), Taichong (LR3), Zhaohai (KI6) and Qichong (ST30) while the control group will receive acupuncture at non-acupoints. The trial will include three menstrual cycles of treatment and three menstrual cycles of follow-up. The primary outcome is pelvic pain that will be assessed by means of a 10-cm visual analog scale (VAS). At each stage, we will evaluate the safety of the acupuncture treatment. DISCUSSION: The study will compare the effectiveness and safety of acupuncture with comfort needles on pelvic pain related to endometriosis in the hope of providing significant evidence for using acupuncture on pelvic pain related to endometriosis.

trial registrationClinicalTrials.gov, ID: NCT03125304 . Registered on 30 April 2017.

Indexed as

Acupuncture TherapyAdultChinaEndometriosisFemaleHumansMulticenter Studies as TopicPain MeasurementPelvic PainRandomized Controlled Trials as TopicSingle-Blind MethodTime FactorsTreatment OutcomeYoung AdultAcupunctureEndometriosisPelvic painStudy protocol

Identifiers

PMID29880009
PMCPMC5992761
OpenAlexW2805536331

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.