ArticleAsian-Australasian journal of animal sciences2018
The identification of novel regions for reproduction trait in Landrace and Large White pigs using a single step genome-wide association study.
Article in Asian-Australasian journal of animal sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Integrated genome-wide association studies, meta-analysis, and Bayesian fine mapping reveal novel quantitative trait loci's and functional candidate genes for vulva traits in large white pigs.Journal of animal science · 2025Pooled it
- Pooled it
- RAPID COMMUNICATION: Multi-breed validation study unraveled genomic regions associated with puberty traits segregating across tropically adapted breeds1.Journal of animal science · 2019Pooled it
- Analysis of the Genetic Diversity and Genetic Structure of Jiangshan Black Pigs Using Single Nucleotide Polymorphism (SNP) Chips.Animals : an open access journal from MDPI · 2024Article
- Effect of SNPs on Litter Size in Swine.Current issues in molecular biology · 2024Article
- Article
- Identification of the genetic basis of sow pelvic organ prolapse.Frontiers in genetics · 2023Article
- Identification of Genomic Regions and Candidate Genes for Litter Traits in French Large White Pigs Using Genome-Wide Association Studies.Animals : an open access journal from MDPI · 2022Article
- Genotype-by-environment interactions for reproduction, body composition, and growth traits in maternal-line pigs based on single-step genomic reaction norms.Genetics, selection, evolution : GSE · 2021Article
- Genome-Wide Association Study for Body Length, Body Height, and Total Teat Number in Large White Pigs.Frontiers in genetics · 2021Article
- Host Genetics of Response to Porcine Reproductive and Respiratory Syndrome in Sows: Reproductive Performance.Frontiers in genetics · 2021Article
- A genome-wide association study of reproduction traits in four pig populations with different genetic backgrounds.Asian-Australasian journal of animal sciences · 2020Article
- Review
- A Genome-Wide Association Study for Calving Interval in Holstein Dairy Cows Using Weighted Single-Step Genomic BLUP Approach.Animals : an open access journal from MDPI · 2020Article
- Genomics of Heat Tolerance in Reproductive Performance Investigated in Four Independent Maternal Lines of Pigs.Frontiers in genetics · 2020Article
- Characterization of Autozygosity in Pigs in Three-Way Crossbreeding.Frontiers in genetics · 2020Article
- Analysis of genetic characteristics of pig breeds using information on single nucleotide polymorphisms.Asian-Australasian journal of animal sciences · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of this study was to investigate a single step genome-wide association study (ssGWAS) for identifying genomic regions affecting reproductive traits in Landrace and Large White pigs.
methodsThe traits included the number of pigs weaned per sow per year (PWSY), the number of litters per sow per year (LSY), pigs weaned per litters (PWL), born alive per litters (BAL), non-productive day (NPD) and wean to conception interval per litters (W2CL). A total of 321 animals (140 Landrace and 181 Large White pigs) were genotyped with the Illumina Porcine SNP 60k BeadChip, containing 61,177 single nucleotide polymorphisms (SNPs), while multiple traits single-step genomic BLUP method was used to calculate variances of 5 SNP windows for 11,048 Landrace and 13,985 Large White data records.
resultsThe outcome of ssGWAS on the reproductive traits identified twenty-five and twenty-two SNPs associated with reproductive traits in Landrace and Large White, respectively. Three known genes were identified to be candidate genes in Landrace pigs including retinol binding protein 7, and ubiquitination factor E4B genes for PWL, BAL, W2CL, and PWSY and one gene, solute carrier organic anion transporter family member 6A1, for LSY and NPD. Meanwhile, five genes were identified to be candidate genes in Large White, two of which, aldehyde dehydrogenase 1 family member A3 and leucine rich repeat kinase 1, associated with all of six reproduction traits and three genes; retrotransposon Gag like 4, transient receptor potential cation channel subfamily C member 5, and LHFPL tetraspan subfamily member 1 for five traits except W2CL.
conclusionThe genomic regions identified in this study provided a start-up point for marker assisted selection and estimating genomic breeding values for improving reproductive traits in commercial pig populations.
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