Observational studyMedicine2018
Association between muscle strength and type 2 diabetes mellitus in adults in Korea: Data from the Korea national health and nutrition examination survey (KNHANES) VI.
Observational study in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- Health-related physical fitness in women with polycystic ovary syndrome versus controls: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- Study of Wrist Joint Movements, Hand Dimensions, and Comparison to Grip Strength Among Omani Medical Students: A Pilot Study.Journal of functional morphology and kinesiology · 2026Article
- Article
- The Relationship between HbA1c Levels and Leg Muscle Strength and Body Flexibility in Diabetes Mellitus Patients.Acta medica Philippina · 2026Article
- Adherence to physical activity guidelines and all-cause and cardiovascular disease mortality in individuals with and without type 2 diabetes.Journal of diabetes and metabolic disorders · 2025Article
- Visceral Adiposity and Lower-Body Strength and Endurance in Women: Correlations Using BIA and the Chair Stand Test.Healthcare (Basel, Switzerland) · 2025Article
- Associations between dynapenic abdominal obesity and diabetes in middle aged and older Chinese.Scientific reports · 2025Article
- Relative Grip Strength as a Screening Indicator for Metabolic Syndrome in Korean Adults: A Cross-Sectional Study Using Data from KNHANES.Medicina (Kaunas, Lithuania) · 2025Article
- Association between total bilirubin and sarcopenia in people with type 2 diabetes: The KAMOGAWA-A study.Endocrine journal · 2025Article
- Grip strength, metabolic syndrome, and type 2 diabetes mellitus: a prospective study.Journal of diabetes and metabolic disorders · 2025Article
- Association of Handgrip Strength with Diabetes, Hypertension, and Comorbidities in a Korean Population: A Large-Scale Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Muscle quality index is correlated with insulin resistance and type 2 diabetes mellitus: a cross-sectional population-based study.BMC public health · 2025Article
- Isokinetic assessment of muscle function according to physical activity level and cardiovascular risk in asymptomatic adults aged 20 to 80 years.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Article
- Muscle Mass and Muscle Strength in Non-Dialysis-Dependent Chronic Kidney Disease Patients.Journal of clinical medicine · 2024Article
- Sex differences in upper and lower strength and their association with body composition among university students.Physical activity and nutrition · 2024Article
- The impact of handgrip strength and waist circumference on glycemic control: Prospective, observational study using outpatient clinical data in Japanese patients with type 2 diabetes mellitus.Journal of diabetes investigation · 2024Observational
- Intra-Individual Variations in How Insulin Sensitivity Responds to Long-Term Exercise: Predictions by Machine Learning Based on Large-Scale Serum Proteomics.Metabolites · 2024Article
- Identifying characteristics and clinical conditions associated with hand grip strength in adults: the Project Baseline Health Study.Scientific reports · 2024Article
- Association of Combining Diet and Physical Activity on Sarcopenia and Obesity in Elderly Koreans with Diabetes.Nutrients · 2024Article
- Association of physiological factors with grip and leg extension strength: tohoku medical megabank community-based cohort study.BMC public health · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus (DM) is a significant chronic disease, and health burden from DM is increasing. Recently, studies on the relationship between handgrip strength, which is a measuring tool for muscle strength, and type 2 DM were published. However, the results have been conflicting. In addition, few studies that used data from adults in Korea have been conducted. Thus, this study aimed to identify the association between handgrip strength as well as type 2 DM and insulin resistance in adults using data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2014 to 2015. Inflammation is a condition affecting the muscle strength of individuals with type 2 DM; therefore, its mediating effects were also examined.We included 8208 participants aged between 19 and 80 years who had undergone a handgrip test and had received information about type 2 DM. General linear and binary logistic regression models were used to examine the association between handgrip strength and type 2 DM variables. In addition, mediation analysis was conducted to estimate the role of inflammation in the relationship between handgrip strength and type 2 DM.After adjusting for age, sex, education, alcohol consumption, lifetime smoking, obesity, and aerobic physical activity, handgrip strength was inversely associated with fasting glucose, HbA1c, and fasting insulin levels as well as the homeostasis model assessment of insulin resistance (HOMA-IR) score. Multivariable logistic regression analyses showed that handgrip strength was significantly inversely associated with type 2 DM and insulin resistance. The high-sensitivity C-reactive protein (hs-CRP), an inflammation-related biomarker, mediated approximately 10% of the association between handgrip strength and type 2 DM.Using large, well-defined, nationally representative cross-sectional data on adults in Korea, we found that handgrip strength, which is an indicator of muscle strength, was associated with type 2 DM.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.