ReviewJournal of applied physiology (Bethesda, Md. : 1985)2018
Competition for blood flow distribution between respiratory and locomotor muscles: implications for muscle fatigue.
Review in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.
- The effect of inspiratory muscle training on the inspiratory muscle metaboreflex: A systematic review.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2025Pooled it
- Effects of combining forearm postexercise muscle ischemia with inspiratory loading on cardiovascular and muscle oxygenation responses.European journal of applied physiology · 2026Trial
- Influence of an inspiratory muscle fatigue protocol on older adults on respiratory muscle strength, muscle oxygen saturation, and functional capacity: a randomized controlled trial.BMC geriatrics · 2024Trial
- Influence of an inspiratory muscle fatigue protocol on healthy youths on respiratory muscle strength, vertical jump performance and muscle oxygen saturation: a randomized controlled trial.Journal of translational medicine · 2024Trial
- The Effect of Adding Noninvasive Ventilation to High-Intensity Exercise on Peripheral and Respiratory Muscle Oxygenation.Respiratory care · 2023Trial
- Influence of graded hypercapnia on endurance exercise performance in healthy humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Trial
- Acute L-Citrulline Supplementation Increases Nitric Oxide Bioavailability but Not Inspiratory Muscle Oxygenation and Respiratory Performance.Nutrients · 2021Trial
- Combined respiratory muscle training and photobiomodulation improve systemic and tissue-specific redox homeostasis in a rat model of type 2 diabetes.Acta diabetologica · 2026Article
- Morphological and functional characterization of respiratory muscles in male runners across different race distances: an ultrasound and physiological assessment.BMC sports science, medicine & rehabilitation · 2026Article
- Inspiratory Muscle Training in Older Patients With Acute Heart Failure: Design and Rationale of a Multi-Arm Parallel-Group Randomized Controlled Trial.Circulation reports · 2026Article
- Respiratory muscle training attenuates oxidative stress and improves antioxidant activity in diabetic rats induced by high-fat diet and low-dose streptozotocin.European journal of applied physiology · 2026Article
- The Influence of Menstrual Cycle Phase on the Physiological and Perceptual Responses to Low-Intensity Continuous and High-Intensity Interval Sessions in Endurance Trained Women: The FENDURA Project.European journal of sport science · 2026Article
- Obligatory neural feedback control of exercise cardiorespiratory function and performance.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Review
- The hyperaemic and metaboreflex response of the diaphragm during fatiguing diaphragmatic work in humans.The Journal of physiology · 2025Article
- Influence of a diaphragmatic fatigue protocol in healthy male population on muscle strength, respiratory function and exercise capacity: A randomized clinical trial.Journal of exercise science and fitness · 2025Article
- Cerebral haemodynamic responses to inspiratory muscle work.Experimental physiology · 2025Article
- Responses to Voluntary Isocapnic Hyperpnea in Normoxia and Hypoxia: Insights from Blood Gas Analysis.Biology · 2025Article
- Polarized or threshold training: is there a superior training intensity distribution to improve V̇OJournal of physiology and biochemistry · 2025Article
- A critical assessment of sympathetic restraint in submaximal exercise: Implications for integrated cardiovascular circuit control in exercise.Experimental physiology · 2025Review
- Improvement in oxygen dynamics after 3 months of home-based respiratory muscle rehabilitation in a patient with complex severe pulmonary hypertension: A case report.Chronic diseases and translational medicine · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sympathetically induced vasoconstrictor modulation of local vasodilation occurs in contracting skeletal muscle during exercise to ensure appropriate perfusion of a large active muscle mass and to maintain also arterial blood pressure. In this synthesis, we discuss the contribution of group III-IV muscle afferents to the sympathetic modulation of blood flow distribution to locomotor and respiratory muscles during exercise. This is followed by an examination of the conditions under which diaphragm and locomotor muscle fatigue occur. Emphasis is given to those studies in humans and animal models that experimentally changed respiratory muscle work to evaluate blood flow redistribution and its effects on locomotor muscle fatigue, and conversely, those that evaluated the influence of coincident limb muscle contraction on respiratory muscle blood flow and fatigue. We propose the concept of a "two-way street of sympathetic vasoconstrictor activity" emanating from both limb and respiratory muscle metaboreceptors during exercise, which constrains blood flow and O
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.