ArticleNeuropsychology2018
Cortical thickness and metacognition in cognitively diverse older adults.
Article in Neuropsychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Awareness impairment in Alzheimer's disease and frontotemporal dementia: a systematic MRI review.Journal of neurology · 2023Pooled it
- What are the neural correlates of meta-cognition and anosognosia in Alzheimer's disease? A systematic review.Neurobiology of aging · 2020Pooled it
- Neural correlates of altered insight in frontotemporal dementia: a systematic review.NeuroImage. Clinical · 2019Pooled it
- The Specificity of Metacognition Questionnaire-30 Subdimensions: Findings From Connectome-Based Predictive Modeling.Depression and anxiety · 2025Article
- Metacognition, cortical thickness, and tauopathy in aging.Neurobiology of aging · 2022Article
- Self-awareness for financial decision making abilities is linked to right temporal cortical thickness in older adults.Brain imaging and behavior · 2022Article
- Depression among caregivers of patients with dementia: Associative factors and management approaches.World journal of psychiatry · 2022Review
- Altered metamemory precedes cognitive impairment in subjective cognitive decline with positive amyloid-beta.Frontiers in aging neuroscience · 2022Article
- Alterations in metamemory capacity and neural correlates in a subtype of subjective cognitive decline.NeuroImage. Clinical · 2022Article
- Subjective Cognitive Decline Is More Accurate When Metamemory Is Better.Frontiers in aging neuroscience · 2022Article
- Self-awareness in Dementia: a Taxonomy of Processes, Overview of Findings, and Integrative Framework.Current neurology and neuroscience reports · 2021Review
- Age-related changes in chimpanzee (Pan troglodytes) cognition: Cross-sectional and longitudinal analyses.American journal of primatology · 2021Article
- Neuroimaging Research on Dementia in Brazil in the Last Decade: Scientometric Analysis, Challenges, and Peculiarities.Frontiers in neurology · 2021Review
- Anosognosia in Mild Cognitive Impairment: Lack of Awareness of Memory Difficulties Characterizes Prodromal Alzheimer's Disease.Frontiers in psychiatry · 2021Article
- Functional and Pathological Correlates of Judgments of Learning in Cognitively Unimpaired Older Adults.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- I know that I know nothing: Cortical thickness and functional connectivity underlying meta-ignorance ability in pre-schoolers.Developmental cognitive neuroscience · 2020Article
- Article
- The Petrified Self 10 Years After: Current Evidence forFrontiers in psychology · 2020Review
- Investigating individual differences in chimpanzee mirror self-recognition and cortical thickness: A vertex-based and region-of-interest analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2019Article
- Decreased meta-memory is associated with early tauopathy in cognitively unimpaired older adults.NeuroImage. Clinical · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveMetacognition, or the ability to accurately identify, appraise, and monitor one's deficits, is commonly impaired in Alzheimer's disease (AD). Poor metacognition prevents correct appraisal of a range of physical, cognitive, and emotional symptoms and facilitates anosognosia, which has important clinical implications for individuals (e.g., diminished treatment adherence, increased engagement in high-risk situations) and caregivers (e.g., higher burden). However, the neural correlates of metacognitive disturbance are still debated in the literature, partly because of the subjective nature of traditional awareness measures.
methodAn objective Feeling of Knowing (FOK) task was used to measure metamemory capacity in a group of cognitively diverse older adults, including 14 with mild to moderate AD and 20 cognitively healthy older adults. The association between three different objective metamemory measures of the FOK task and regional cortical thickness (12 bilateral regions of interest [ROIs] hypothesized to support self-awareness) was analyzed using partial correlations.
resultsLess accurate metamemory at the local and global levels was associated with reduced right posterior cingulate cortical thickness, r = -0.42, p = .02 and reduced right medial prefrontal, r = -0.39, p = .029, respectively.
conclusionsTo our knowledge, this was the first study to examine metacognition in relation to cortical thickness. Both global and local metamemory functions appear to rely on the integrity of right sided midline regions, known to be important for processing self-referential information. Findings are conceptualized with regard to the Default Mode Network, and also considered in relation to recent findings pointing to the right insula as a region critical for self-awareness. (PsycINFO Database Record
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.