ArticleNucleic acids research2018
LOLAweb: a containerized web server for interactive genomic locus overlap enrichment analysis.
Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- RegRegSEA: a web server for regulatory region set enrichment analysis of epigenomic data.Nucleic acids research · 2026Article
- Distinct Regulatory DNA Methylation Signatures Across Multiple Sclerosis, Neuromyelitis Optica, and Neurological Post-Acute Sequelae of COVID-19.Journal of clinical medicine · 2026Article
- ATACdb 2.0: a comprehensive chromatin accessibility database of human and mouse.Nucleic acids research · 2026Article
- 3D enhancer architecture coordinated by CTCF determines immune-related gene expression patterns via RNA polymerase II pause-release in CD4+ T cells.Nucleic acids research · 2025Article
- Growth of human regulatory CD4iScience · 2025Article
- Methods for constructing and evaluating consensus genomic interval sets.Nucleic acids research · 2024Article
- Joint Representation Learning for Retrieval and Annotation of Genomic Interval Sets.Bioengineering (Basel, Switzerland) · 2024Article
- PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer.Nucleic acids research · 2023Article
- RgnTX: Colocalization analysis of transcriptome elements in the presence of isoform heterogeneity and ambiguity.Computational and structural biotechnology journal · 2023Article
- Dynamic transcriptional activity and chromatin remodeling of regulatory T cells after varied duration of interleukin-2 receptor signaling.Nature immunology · 2022Article
- GenomicDistributions: fast analysis of genomic intervals with Bioconductor.BMC genomics · 2022Article
- FILER: a framework for harmonizing and querying large-scale functional genomics knowledge.NAR genomics and bioinformatics · 2022Article
- A brief survey of tools for genomic regions enrichment analysis.Frontiers in bioinformatics · 2022Review
- Integrated evaluation of telomerase activation and telomere maintenance across cancer cell lines.eLife · 2021Article
- Bedshift: perturbation of genomic interval sets.Genome biology · 2021Article
- Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences.Nucleic acids research · 2021Article
- Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB.Scientific reports · 2021Article
- Recommendations for the FAIRification of genomic track metadata.F1000Research · 2021Article
- Heterogeneity in the Epigenetic Landscape of Murine Testis-Specific Histone Variants TH2A and TH2B Sharing the Same Bi-Directional Promoter.Frontiers in cell and developmental biology · 2021Article
- GeneTrail 3: advanced high-throughput enrichment analysis.Nucleic acids research · 2020Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The past few years have seen an explosion of interest in understanding the role of regulatory DNA. This interest has driven large-scale production of functional genomics data and analytical methods. One popular analysis is to test for enrichment of overlaps between a query set of genomic regions and a database of region sets. In this way, new genomic data can be easily connected to annotations from external data sources. Here, we present an interactive interface for enrichment analysis of genomic locus overlaps using a web server called LOLAweb. LOLAweb accepts a set of genomic ranges from the user and tests it for enrichment against a database of region sets. LOLAweb renders results in an R Shiny application to provide interactive visualization features, enabling users to filter, sort, and explore enrichment results dynamically. LOLAweb is built and deployed in a Linux container, making it scalable to many concurrent users on our servers and also enabling users to download and run LOLAweb locally.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.