SynthesisThe Journal of antimicrobial chemotherapy2018
Towards a global definition of responsible antibiotic use: results of an international multidisciplinary consensus procedure.
Synthesis in The Journal of antimicrobial chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The vicious cycle of the public's irrational use of antibiotics for upper respiratory tract infections: A mixed methods systematic review.Frontiers in public health · 2022Pooled it
- Quality indicators for responsible antibiotic use in the inpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.The Journal of antimicrobial chemotherapy · 2018Pooled it
- Quality indicators assessing antibiotic use in the outpatient setting: a systematic review followed by an international multidisciplinary consensus procedure.The Journal of antimicrobial chemotherapy · 2018Pooled it
- Variation in antibiotic use among and within different settings: a systematic review.The Journal of antimicrobial chemotherapy · 2018Pooled it
- Antimicrobial prescribing guidelines for feedlot cattle.Australian veterinary journal · 2026Article
- From Host-Derived Pressures to the Environmental Anti-Antimicrobial Peptides Resistome: Mechanisms, Reservoirs and Implications for Therapeutic Peptide Design.Marine drugs · 2026Review
- Plan-do-check-act (PDCA) cycle analysis for antimicrobial stewardship of orthopedic patients in trauma center-implementation research.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- DOSAGE: Dataset for Optimized Safe Antibiotic Guidelines and Estimates.Scientific data · 2025Article
- An in-depth analysis of antimicrobial prescription quality in 10 non-university hospitals, in southwest Germany, 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024Article
- Antimicrobial stewardship: a definition with a One Health perspective.npj antimicrobials and resistance · 2024Review
- Article
- Assessment of Antimicrobial Consumption in Multi-Field Hospitals with Pediatric Inpatients: Conventional vs. Novel Pediatric-Adjusted Methodologies.Antibiotics (Basel, Switzerland) · 2023Article
- Planning and Reporting Effective Web-Based RAND/UCLA Appropriateness Method Panels: Literature Review and Preliminary Recommendations.Journal of medical Internet research · 2022Review
- Optimizing antibiotic use in Indonesia: A systematic review and evidence synthesis to inform opportunities for intervention.The Lancet regional health. Southeast Asia · 2022Article
- Unraveling the Nature of Antibiotics: Is It a Cure or a New Hurdle to the Patient Treatment?Cureus · 2022Review
- The General Population's Inappropriate Behaviors and Misunderstanding of Antibiotic Use in China: A Systematic Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2021Review
- Assessment of Appropriateness of Antimicrobial Therapy in Resource-Constrained Settings: Development and Piloting of a Novel Tool-AmRAT.Antibiotics (Basel, Switzerland) · 2021Article
- Organization of antibiotic stewardship in Europe: the way to go.Wiener medizinische Wochenschrift (1946) · 2021Article
- Non-compliance with clinical guidelines increases the risk of complications after primary total hip and knee joint replacement surgery.PloS one · 2021Article
- Challenges and research priorities to progress the impact of antimicrobial stewardship.Drugs in context · 2019Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Conducted as part of the Driving Reinvestment in Research and Development and Responsible Antibiotic Use (DRIVE-AB) project, this study aimed to identify key elements for a global definition of responsible antibiotic use based on diverse stakeholder input. Methods: A three-step RAND-modified Delphi method was applied. First, a systematic review of antibiotic stewardship literature and relevant organization web sites identified definitions and synonyms of responsible use. Identified elements of definitions were presented by questionnaire to a multidisciplinary international stakeholder panel for appraisal of their relevance. Finally, questionnaire results were discussed in a consensus meeting. Results: The systematic review and the web site search identified 17 synonyms (e.g. appropriate, correct) and 22 potential elements to include in a definition of responsible use. Elements were grouped into patient-level (e.g. Indication, Documentation) or societal-level elements (e.g. Education, Future Effectiveness). Forty-eight stakeholders with diverse backgrounds [medical community, public health, patients, antibiotic research and development (R&D), regulators, governments] from 18 countries across all continents participated in the questionnaire. Based on relevance scores, 21 elements were retained, 9 were rephrased and 1 was added. Together, the 22 elements and associated best-practice descriptions comprise an exhaustive list of elements to be considered when defining responsible use. Conclusions: Combination of concepts from the literature and stakeholder opinion led to an international multidisciplinary consensus on a global definition of responsible antibiotic use. The widely diverging perspectives of stakeholders providing input should ensure the comprehensiveness and relevance of the definition for both individual patients and society. An aspirational goal would be to address all elements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.