ArticleGenome biology and evolution2018
Genome Survey of the Freshwater Mussel Venustaconcha ellipsiformis (Bivalvia: Unionida) Using a Hybrid De Novo Assembly Approach.
Article in Genome biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Beyond Genetic Indicators: How Reproductive Mode and Hybridisation Challenge Freshwater Mussel Conservation.Molecular ecology · 2025Article
- Chromosome-level genome assembly of the freshwater mussel Sinosolenaia oleivora (Heude, 1877).Scientific data · 2024Article
- The transcriptome assembly of the European freshwater mussel Unio elongatulus C. Pfeiffer, 1825.Scientific data · 2024Article
- The First High-Quality Genome Assembly of Freshwater Pearl MusselInternational journal of molecular sciences · 2024Article
- PacBio Hi-Fi genome assembly of the Iberian dolphin freshwater mussel Unio delphinus Spengler, 1793.Scientific data · 2023Article
- Article
- Strong, Recent Selective Sweeps Reshape Genetic Diversity in Freshwater Bivalve Megalonaias nervosa.Molecular biology and evolution · 2023Article
- The Crown Pearl V2: an improved genome assembly of the European freshwater pearl musselGigaByte (Hong Kong, China) · 2023Article
- The gill transcriptome of threatened European freshwater mussels.Scientific data · 2022Article
- The genome of the zebra mussel, Dreissena polymorpha: a resource for comparative genomics, invasion genetics, and biocontrol.G3 (Bethesda, Md.) · 2022Article
- The male-type mitochondrial genome of the freshwater musselMitochondrial DNA. Part B, Resources · 2022Article
- MODB: a comprehensive mitochondrial genome database for Mollusca.Database : the journal of biological databases and curation · 2021Article
- The genome of the Pyrenean desman and the effects of bottlenecks and inbreeding on the genomic landscape of an endangered species.Evolutionary applications · 2021Article
- Molluscan phylogenomics requires strategically selected genomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Gene family amplification facilitates adaptation in freshwater unionid bivalve Megalonaias nervosa.Molecular ecology · 2021Article
- New microsatellite markers for Ellipse, Venustaconcha ellipsiformis (Bivalvia: Unionidae), with notes on optimal sample size and cross-species amplification.Molecular biology reports · 2021Article
- A High-Quality Reference Genome for a Parasitic Bivalve with Doubly Uniparental Inheritance (Bivalvia: Unionida).Genome biology and evolution · 2021Article
- The Iron-Responsive Genome of the Chiton Acanthopleura granulata.Genome biology and evolution · 2021Article
- Exploring Satellite DNAs: Specificities of Bivalve Mollusks Genomes.Progress in molecular and subcellular biology · 2021Article
- Reconstruction of ancient homeobox gene linkages inferred from a new high-quality assembly of the Hong Kong oyster (Magallana hongkongensis) genome.BMC genomics · 2020Article
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Authors and funding
9 authors.
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Abstract
Freshwater mussels (Bivalvia: Unionida) serve an important role as aquatic ecosystem engineers but are one of the most critically imperilled groups of animals. Here, we used a combination of sequencing strategies to assemble and annotate a draft genome of Venustaconcha ellipsiformis, which will serve as a valuable genomic resource given the ecological value and unique "doubly uniparental inheritance" mode of mitochondrial DNA transmission of freshwater mussels. The genome described here was obtained by combining high-coverage short reads (65× genome coverage of Illumina paired-end and 11× genome coverage of mate-pairs sequences) with low-coverage Pacific Biosciences long reads (0.3× genome coverage). Briefly, the final scaffold assembly accounted for a total size of 1.54 Gb (366,926 scaffolds, N50 = 6.5 kb, with 2.3% of "N" nucleotides), representing 86% of the predicted genome size of 1.80 Gb, while over one third of the genome (37.5%) consisted of repeated elements and >85% of the core eukaryotic genes were recovered. Given the repeated genetic bottlenecks of V. ellipsiformis populations as a result of glaciations events, heterozygosity was also found to be remarkably low (0.6%), in contrast to most other sequenced bivalve species. Finally, we reassembled the full mitochondrial genome and found six polymorphic sites with respect to the previously published reference. This resource opens the way to comparative genomics studies to identify genes related to the unique adaptations of freshwater mussels and their distinctive mitochondrial inheritance mechanism.
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