Evidence map›Paper›PMID 29878087›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2019

Time to hospital arrival among patients with acute myocardial infarction in China: a report from China PEACE prospective study.

Wenchi Guan, Arjun K Venkatesh, Xueke Bai, Si Xuan, Jing Li, Xi Li, Haibo Zhang, Xin Zheng, Frederick A Masoudi, John A Spertus and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in European heart journal. Quality of care & clinical outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01624909 (The China PEACE), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01624909 completednot on this map

The China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) Prospective Study of Acute Myocardial Infarction

TypeobservationalSponsorChina National Center for Cardiovascular DiseasesRan2012 to 2015Enrolled4,286ConditionsCoronary Heart Disease
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Discovery of vasodilatory effects of NaActa pharmacologica Sinica · 2026
    Article
  3. Article
  4. Factors Influencing Time to First Medical Contact in Patients with Acute ST-Segment Elevation Myocardial Infarction: A Retrospective Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Cytokine storm: behind the scenes of the collateral circulation after acute myocardial infarction.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. Article
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  15. Article
  16. Review
  17. Article
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenchi GuanNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, China.
Arjun K VenkateshCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, 1 Church Street, Suite 200, New Haven, CT, USA.
Xueke BaiNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, China.
Si XuanDepartment of Pharmaceutical & Health Economics, School of Pharmacy, University of Southern California, 635 Downey Way, Los Angeles, California, USA.
Jing LiNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, China.
Xi LiNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, China.
Haibo ZhangNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, China.
Xin ZhengNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, China.
Frederick A MasoudiDivision of Cardiology, University of Colorado Anschutz Medical Campus, Campus Box B132, 12401 East 17th Avenue, Room 522, Aurora, CO, USA.
John A SpertusSaint Luke's Mid America Heart Institute/University of Missouri Kansas City, 4401 Wornall Road, Kansas City, MO, USA.
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, 1 Church Street, Suite 200, New Haven, CT, USA.
Lixin JiangNational Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing, China.

Funding

Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
Yale University Clinical and Translational Science Award ProgramKL2TR000140 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$2.9M
NCATS NIH HHS KL2 TR000140NCATS NIH HHS KL2 TR001862
6 · The paper itself

Abstract

Aims: Few contemporary studies have reported the time between acute myocardial infarction (AMI) symptoms onset and hospital arrival, associated factors, and patient perceptions of AMI symptoms and care seeking. We sought to study these issues using data from China, where AMI hospitalizations are increasing. Methods and results: We used data from the China PEACE prospective AMI study of 53 hospitals across 21 provinces in China. Patients were interviewed during index hospitalization for information of symptom onset, and perceived barriers to accessing care. Regression analyses were conducted to explore factors associated with the time between symptom onset and hospital arrival. The final sample included 3434 patients (mean age 61 years). The median time from symptom onset to hospital arrival was 4 h (interquartile range 2-7.5 h). While 94% of patients reported chest pain or chest discomfort, only 43% perceived symptoms as heart-related. In multivariable analyses, time to hospital arrival was longer by 14% and 39% for patients failing to recognize symptoms as cardiac and those with rural medical insurance, respectively (both P < 0.001). Compared with patients with household income over 100 000 RMB, those with income of 10 000-50 000 RMB, and <10 000 RMB had 16% and 23% longer times, respectively (both P = 0.03). Conclusion: We reported an average time to hospital arrival of 4 h for AMI in China, with longer time associated with rural medical insurance, failing to recognize symptoms as cardiac, and low household income. Strategies to improve the timeliness of presentation may be essential to improving outcomes for AMI in China. Clinical trial registration: https://clinicaltrials.gov/ct2/show/NCT01624909.

Indexed as

Emergency Service, HospitalPatient Acceptance of Health CareTime-to-TreatmentAgedChinaFemaleHealth Services AccessibilityHumansIncomeInsurance, HealthMaleMiddle AgedMyocardial InfarctionProspective StudiesRural PopulationTime Factors

Identifiers

PMID29878087
PMCPMC6307335

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.