Evidence map›Paper›PMID 29878062›Full record

Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2018

Improving Adherence to Smoking Cessation Treatment: Smoking Outcomes in a Web-based Randomized Trial.

Amanda L Graham, George D Papandonatos, Sarah Cha, Bahar Erar, Michael S Amato

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01544153 (Improving Adherence to Web-Based Cessation Programs), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01544153 nacompletednot on this map

Improving Adherence to Web-Based Cessation Programs: A Social Network Approach

TypeinterventionalSponsorTruth InitiativeRan2012 to 2017Enrolled5,292ConditionsSmoking CessationArmsWEB, Social Network, Nicotine Replacement Therapy (NRT)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Nicotine replacement therapy versus control for smoking cessation.The Cochrane database of systematic reviews · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amanda L GrahamSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC, USA.
George D PapandonatosDepartment of Biostatistics, Brown University School of Public Health, Providence, RI, USA.
Sarah ChaSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC, USA.
Bahar ErarDepartment of Biostatistics, Brown University School of Public Health, Providence, RI, USA.
Michael S AmatoSchroeder Institute for Tobacco Research and Policy Studies, Truth Initiative, Washington, DC, USA.
American Legacy Foundation · USBrown University · US

Funding

Improving Adherence to Web-based Cessation Programs: A Social Network ApproachR01CA155489 · NCI · TRUTH INITIATIVE FOUNDATION · PI GRAHAM, AMANDA L · 2011 to 2015
$2.6M
NCI NIH HHS R01 CA155489
6 · The paper itself

Abstract

Background: Partial adherence in Internet smoking cessation interventions presents treatment and evaluation challenges. Increasing adherence may improve outcomes. Purpose: To present smoking outcomes from an Internet randomized trial of two strategies to encourage adherence to tobacco dependence treatment components: (i) a social network (SN) strategy to integrate smokers into an online community and (ii) free nicotine replacement therapy (NRT). In addition to intent-to-treat analyses, we used novel statistical methods to distinguish the impact of treatment assignment from treatment utilization. Methods: A total of 5,290 current smokers on a cessation website (WEB) were randomized to WEB, WEB + SN, WEB + NRT, or WEB + SN + NRT. The main outcome was 30-day point prevalence abstinence at 3 and 9 months post-randomization. Adherence measures included self-reported medication use (meds), and website metrics of skills training (sk) and community use (comm). Inverse Probability of Retention Weighting and Inverse Probability of Treatment Weighting jointly addressed dropout and treatment selection. Propensity weights were used to calculate Average Treatment effects on the Treated. Results: Treatment assignment analyses showed no effects on abstinence for either adherence strategy. Abstinence rates were 25.7%-32.2% among participants that used all three treatment components (sk+comm +meds).Treatment utilization analyses revealed that among such participants, sk+comm+meds yielded large percentage point increases in 3-month abstinence rates over sk alone across arms: WEB = 20.6 (95% CI = 10.8, 30.4), WEB + SN = 19.2 (95% CI = 11.1, 27.3), WEB + NRT = 13.1 (95% CI = 4.1, 22.0), and WEB + SN + NRT = 20.0 (95% CI = 12.2, 27.7). Conclusions: Novel propensity weighting approaches can serve as a model for establishing efficacy of Internet interventions and yield important insights about mechanisms. Clinical Trials.gov: NCT01544153.

Indexed as

Social NetworkingAdultBehavior TherapyCombined Modality TherapyHumansInternetModels, StatisticalOutcome Assessment, Health CarePatient Acceptance of Health CarePatient ComplianceSmoking CessationSmoking Cessation AgentsTobacco Use Cessation DevicesSmoking Cessation Agents

Identifiers

PMID29878062
PMCPMC6037305
OpenAlexW2792532026

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.