ArticleAmerican journal of epidemiology2018
Revealing Measles Outbreak Risk With a Nested Immunoglobulin G Serosurvey in Madagascar.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of measles IgG enzyme immunoassays (EIA) versus plaque reduction neutralization test (PRNT) for measuring measles serostatus: a systematic review of head-to-head analyses of measles IgG EIA and PRNT.BMC infectious diseases · 2023Pooled it
- Seroprevalence of measles immunoglobulin G antibodies in Bahrain: A cross-sectional study using fever and rash surveillance data (2021-2025).IJID regions · 2026Article
- Molecular Characterization of Measles and Rubella Virus Strains from the 2018-2019 Epidemic in Madagascar.Pathogens (Basel, Switzerland) · 2026Article
- Revealing trends in measles immunity during periods of varying measles circulation in Madagascar.American journal of epidemiology · 2025Article
- Serological survey to determine measles and rubella immunity gaps across age and geographic locations in The Gambia: a study protocol.Global health action · 2025Article
- The Use of Residual Blood Specimens in Seroprevalence Studies for Vaccine-Preventable Diseases: A Scoping Review.Vaccines · 2025Review
- serosim: An R package for simulating serological data arising from vaccination, epidemiological and antibody kinetics processes.PLoS computational biology · 2023Article
- Evaluating the effect of measles and rubella mass vaccination campaigns on seroprevalence in India: a before-and-after cross-sectional household serosurvey in four districts, 2018-2020.The Lancet. Global health · 2022Article
- Leveraging a national biorepository in Zambia to assess measles and rubella immunity gaps across age and space.Scientific reports · 2022Article
- Impact of health system strengthening on delivery strategies to improve child immunisation coverage and inequalities in rural Madagascar.BMJ global health · 2022Article
- The Challenge of Achieving Immunity Through Multiple-Dose Vaccines in Madagascar.American journal of epidemiology · 2021Article
- Article
- The impact of COVID-19 nonpharmaceutical interventions on the future dynamics of endemic infections.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Using Serology with Models to Clarify the Trajectory of the SARS-CoV-2 Emerging Outbreak.Trends in immunology · 2020Article
- Towards better targeting: lessons from a posthoneymoon measles outbreak in Madagascar, 2018-2019.BMJ global health · 2020Article
- Using Serology to Anticipate Measles Post-honeymoon Period Outbreaks.Trends in microbiology · 2020Article
- Review
- Recent setbacks in measles elimination: the importance of investing in innovations for immunizations.The Pan African medical journal · 2020Article
- Article
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Authors and funding
11 authors.
Funding
Abstract
Madagascar reports few measles cases annually and high vaccination campaign coverage. However, the underlying age profile of immunity and risk of a measles outbreak is unknown. We conducted a nested serological survey, testing 1,005 serum samples (collected between November 2013 and December 2015 via Madagascar's febrile rash surveillance system) for measles immunoglobulin G antibody titers. We directly estimated the age profile of immunity and compared these estimates with indirect estimates based on a birth cohort model of vaccination coverage and natural infection. Combining these estimates of the age profile of immunity in the population with an age-structured model of transmission, we further predicted the risk of a measles outbreak and the impact of mitigation strategies designed around supplementary immunization activities. The direct and indirect estimates of age-specific seroprevalence show that current measles susceptibility is over 10%, and modeling suggests that Madagascar may be at risk of a major measles epidemic.
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