ArticleCardiovascular journal of Africa
Presentation, management and outcomes of acute coronary syndrome: a registry study from Kenyatta National Hospital in Nairobi, Kenya.
Article in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Acute Coronary Syndromes in Sub-Saharan Africa: A 10-Year Systematic Review.Journal of the American Heart Association · 2022Pooled it
- Cost-effectiveness of group medical visits and microfinance interventions versus usual care to manage hypertension in Kenya: a secondary modelling analysis of data from the Bridging Income Generation with Group Integrated Care (BIGPIC) trial.The Lancet. Global health · 2024Trial
- Clinical profiles, management, and outcomes of acute coronary syndrome patients in hospitals without reperfusion therapy: a multicentre study in Addis Ababa, Ethiopia.BMC cardiovascular disorders · 2026Article
- In-Hospital mortality and determinants among myocardial infarction patients in public hospitals, Northwest Ethiopia: evidence from sub-Saharan Africa.BMC cardiovascular disorders · 2026Article
- Article
- Performance of the Grace ACS Risk Score in Predicting in-Hospital and Six-Month Mortality in Patients with ACS: A Single Center Retrospective Cohort Study.Vascular health and risk management · 2026Article
- Percutaneous coronary interventions in Sudan: insights from severely influenced conflict zone.Cardiovascular endocrinology & metabolism · 2025Article
- Acute coronary syndrome prevalence and outcomes in a Tanzanian emergency department: Results from a prospective surveillance study.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025Article
- Incidence of bleeding and performance of the PRECISE-DAPT score in predicting bleeding in patients on dual antiplatelet therapy after treatment for acute coronary syndrome in Kenya.BMC cardiovascular disorders · 2025Article
- Management of acute coronary syndrome in resource-limited set up: a summary of 4-year review of two hospitals in Ethiopia.Frontiers in cardiovascular medicine · 2025Article
- Clinical characteristics and outcomes of patients undergoing percutaneous coronary intervention at Gesund Cardiac and Medical Center, Addis Ababa, Ethiopia, 2024.American journal of cardiovascular disease · 2025Article
- Improving acute myocardial infarction care in northern Tanzania: barrier identification and implementation strategy mapping.BMC health services research · 2024Article
- Adapting an Intervention to Improve Acute Myocardial Infarction Care in Tanzania: Co-Design of the MIMIC Intervention.Annals of global health · 2024Article
- The Pandemic of Coronary Artery Disease in the Sub-Saharan Africa: What Clinicians Need to Know.Current atherosclerosis reports · 2023Review
- Acute coronary syndrome and its treatment outcomes in Ethiopia: a systematic review and meta-analysis.Journal of pharmaceutical policy and practice · 2023Review
- Remote Ischaemic Conditioning in STEMI Patients in Sub-Saharan AFRICA: Rationale and Study Design for the RIC-AFRICA Trial.Cardiovascular drugs and therapy · 2023Article
- [Characteristics and predictive factors of death in acute coronary syndromes among the elderly: data from the Acute coronary syndrome registry at the Abidjan Heart Institute].Medecine tropicale et sante internationale · 2023Article
- In-hospital mortality from acute coronary syndrome in Africa: a systematic review and meta-analysis.SAGE open medicine · 2023Review
- Acute coronary syndromes.Lancet (London, England) · 2022Review
- One-Year Outcomes and Factors Associated With Mortality Following Acute Myocardial Infarction in Northern Tanzania.Circulation. Cardiovascular quality and outcomes · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundAcute coronary syndrome (ACS) is understudied in sub-Saharan Africa despite its increasing disease burden. We sought to create an ACS registry at Kenyatta National Hospital to evaluate the presentation, management and outcomes of ACS patients.
methodsFrom November 2016 to April 2017, we conducted a retrospective review of ACS cases managed at Kenyatta National Hospital between 2013 and 2016, with a primary discharge diagnosis of ACS, based on International Classification of Diseases (ICD) 10 coding (I20-I24). We compared the presentation, management and outcomes by ACS subtype using analysis of variance testing. We created multivariable logistic regression models using the Global Registry of Acute Coronary Events (GRACE) risk score to evaluate the association between clinical variables, including guideline-directed medical therapy and in-hospital outcomes.
resultsAmong 196 ACS admissions, the majority (65%) was male, and the median age was 58 years. Most (57%) ACS admissions were for ST-segment-elevation myocardial infarction (STEMI). In-hospital dual antiplatelet (> 85%), beta-blockade (72%) and anticoagulant (72%) therapy was common. A minority (33%) of patients with STEMI was eligible for reperfusion therapy but only 5% received reperfusion. In-hospital mortality rate was 17%, and highest among individuals presenting with STEMI (21%). After multivariable adjustment, higher serum creatinine level was associated with higher odds of in-hospital death (OR = 1.84, 95% CI: 1.21 - 2.78), and STEMI and Killip class > 1 were associated with in-hospital composite of death, re-infarction, stroke, major bleeding or cardiac arrest (STEMI: OR = 8.70, 95% CI: 2.52 - 29.93; Killip > 1: OR = 10.7, 95% CI: 3.34-34.6).
conclusionsWe describe the largest ACS registry at Kenyatta National Hospital to date and identify potential areas for improved ACS care related to diagnostics and management to optimise in-hospital outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.