Evidence map›Paper›PMID 29877267›Full record

ReviewInternal medicine (Tokyo, Japan)2018

The Analysis of Renal Infiltrating Cells in Acute Tubulointerstitial Nephritis Induced by Anti-PD-1 Antibodies: A Case Report and Review of the Literature.

Akifumi Tabei, Mitsuharu Watanabe, Hidekazu Ikeuchi, Masao Nakasatomi, Toru Sakairi, Yoriaki Kaneko, Akito Maeshima, Kyoichi Kaira, Junko Hirato, Yoshihisa Nojima and 1 more

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Akifumi TabeiDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Mitsuharu WatanabeDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Hidekazu IkeuchiDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Masao NakasatomiDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Toru SakairiDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Yoriaki KanekoDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Akito MaeshimaDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Kyoichi KairaDepartment of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Japan.
Junko HiratoDepartment of Pathology, Gunma University Hospital, Japan.
Yoshihisa NojimaDepartment of Rheumatology and Nephrology, Japan Red Cross Maebashi Hospital, Japan.
Keiju HiromuraDepartment of Nephrology and Rheumatology, Gunma University Graduate School of Medicine, Japan.
Gunma University · JPGunma University Hospital · JPMaebashi Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nivolumab is an anti-programmed cell death-1 (PD-1) antibody that is utilized as an immune checkpoint inhibitor (ICI) for cancer therapy. We herein present the case of a 57-year-old man who developed acute kidney injury during treatment with nivolumab for lung cancer. A renal biopsy revealed acute tubulointerstitial nephritis. Immunohistochemical staining demonstrated marked infiltration of macrophages and T cells together with mild B cell infiltration. Of note, strong CD163

Indexed as

Acute Kidney InjuryAntibodiesAntigens, CDAntigens, Differentiation, MyelomonocyticAntineoplastic Agents, ImmunologicalB7-H1 AntigenB-LymphocytesCD163 AntigenHumansImmunologic FactorsKidneyLung NeoplasmsMacrophagesMaleMiddle AgedNephritis, InterstitialAntibodiesAntigens, CDAntigens, Differentiation, MyelomonocyticAntineoplastic Agents, ImmunologicalB7-H1 AntigenCD163 AntigenCD274 protein, humanImmunologic FactorsNivolumabPrednisoloneProgrammed Cell Death 1 ReceptorReceptors, Cell Surfaceacute tubulointerstitial nephritisanti-PD-1 antibodyimmune checkpoint inhibitorM2 macrophage

Identifiers

PMID29877267
PMCPMC6262704
OpenAlexW2806588963

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.