Evidence map›Paper›PMID 29877264›Full record

ArticleInternal medicine (Tokyo, Japan)2018

A Young Man with Non-alcoholic Steatohepatitis and Serum Anti-mitochondrial Antibody Positivity.

Takuya Seike, Takuya Komura, Yoshiaki Shimizu, Hitoshi Omura, Tatsuo Kumai, Takashi Kagaya, Hajime Ohta, Atsuhiro Kawashima, Kenichi Harada, Shuichi Kaneko and 1 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Takuya SeikeDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Takuya KomuraDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Yoshiaki ShimizuDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Hitoshi OmuraDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Tatsuo KumaiDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Takashi KagayaDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Hajime OhtaDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Atsuhiro KawashimaDepartment of Clinical Laboratory, National Hospital Organization Kanazawa Medical Center, Japan.
Kenichi HaradaDepartment of Human Pathology, Kanazawa University Graduate School of Medical Science, Japan.
Shuichi KanekoSystem Biology, Graduate School of Advanced Preventive Medical Science, Kanazawa University, Japan.
Masashi UnouraDepartment of Gastroenterology, National Hospital Organization Kanazawa Medical Center, Japan.
Kanazawa Medical Center · JPKanazawa University · JPNational Hospital Organization · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 37-year-old obese man who was a social drinker was admitted to our hospital to undergo a detailed examination for liver injury with anti-mitochondrial antibody positivity. Abdominal ultrasonography revealed moderate fatty liver. A histological analysis showed steatosis of approximately 30% of the hepatocytes, focal necrosis, a few ballooning hepatocytes and lobular inflammation suggestive of steatohepatitis, epithelioid granuloma and irregularity of the sequence of the bile duct epithelium accompanied by lymphocyte infiltration suggestive of chronic cholangitis. He was diagnosed with non-alcoholic steatohepatitis complicated with primary biliary cholangitis. His liver injury was improved by weight loss and high-dose ursodeoxycholic acid treatment.

Indexed as

AdultAutoantibodiesChronic DiseaseHumansLiver Cirrhosis, BiliaryMaleMitochondriaNon-alcoholic Fatty Liver DiseaseObesityAutoantibodiesanti-mitochondrial antibodychronic cholangitisnon-alcoholic steatohepatitisprimary biliary cholangitisursodeoxycholic acid

Identifiers

PMID29877264
PMCPMC6262692
OpenAlexW2806236184

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.