Evidence map›Paper›PMID 29877197›Full record

ArticleExperimental animals2018

Association between Helicobacter pylori infection and platelet count in mice.

Teruko Fukuda, Eri Asou, Kimiko Nogi, Masahiko Yasuda, Kazuo Goto

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental animals, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03629587 (Helicobacter Pylori and it's Hematological Impact), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03629587 completednot on this map

Helicobacter Pylori and it's Hematological Impact

TypeobservationalSponsorAssiut UniversityRan2016 to 2018Enrolled100ConditionsH Pylori Infection
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Effect ofBlood research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Teruko FukudaDepartment of Clinical Laboratory Medicine, Teikyo University, 2-1-11 Kaga, Itabashi, Tokyo 173-8605, Japan.
Eri AsouTeikyo University Hospital, 2-1-11 Kaga, Itabashi, Tokyo 173-0005, Japan.
Kimiko NogiTeikyo University Hospital, 2-1-11 Kaga, Itabashi, Tokyo 173-0005, Japan.
Masahiko YasudaPathological Analysis Center, Central Institute for Experimental Animals, 3-25-12 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan.
Kazuo GotoDepartment of Clinical Laboratory Medicine, Teikyo University, 2-1-11 Kaga, Itabashi, Tokyo 173-8605, Japan.
Teikyo University · JPTeikyo University Hospital · JPCentral Institute for Experimental Animals · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strong evidence for an association between idiopathic thrombocytopenic purpura (ITP) and Helicobacter pylori (HP) infection has been reported in humans. Chronic ITP is known to be improved by the eradication of HP. The purpose of this study was to reproduce these events by the experimental infection of several strains of mice with HP. BALB/c, C57BL/6, and DBA/2 mice were untreated or orally inoculated with HP. Two months later, platelet counts were compared in samples from HP-infected and noninfected mice. Platelet counts (mean ± SD, × 10

Indexed as

Disease Models, AnimalHelicobacter InfectionsHelicobacter pyloriPlatelet CountAnimalsAntibodies, BacterialGastritisMaleMice, Inbred BALB CMice, Inbred C57BLMice, Inbred DBAPurpura, Thrombocytopenic, IdiopathicAntibodies, BacterialHelicobacter pyloriinfectionITPmousestrain

Identifiers

PMID29877197
PMCPMC6219882
OpenAlexW2807012741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.