Trial reportPublic health nutrition2018
Effectiveness of zinc-fortified water on zinc intake, status and morbidity in Kenyan pre-school children: a randomised controlled trial.
Trial report in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Zinc for prevention and treatment of the common cold.The Cochrane database of systematic reviews · 2024Pooled it
- Pooled it
- Trial
- Drinking Water Disinfection Using Nutritional Level Zinc Assisted with Electric Field Treatment.Environmental science & technology · 2026Article
- The Role of Zinc in Pediatric Respiratory Infections: Evidence from Clinical Trials and Real-World Studies.Nutrients · 2026Review
- The Policy of Compulsory Large-Scale Food Fortification in Sub-Saharan Africa.Foods (Basel, Switzerland) · 2024Review
- The potential contribution of house crickets to the dietary zinc content and nutrient adequacy in young Kenyan children: a linear programming analysis using Optifood.The British journal of nutrition · 2023Article
- Source apportionment of micronutrients in the diets of Kilimanjaro,Tanzania and Counties of Western Kenya.Scientific reports · 2019Article
- Soil Zinc Is Associated with Serum Zinc But Not with Linear Growth of Children in Ethiopia.Nutrients · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveZn deficiency and diarrhoea are prevalent and may coexist in children living in low-resource settings. Recently, a novel approach for delivering Zn via microbiologically treated, Zn-fortified water was shown to be effective in improving Zn status in West African schoolchildren. We assessed the effectiveness of Zn-fortified, microbiologically purified water delivered as a household intervention on Zn intake, status and morbidity in children aged 2-6 years from rural western Kenya.
designRandomised controlled trial. Intervention included households assigned to water treatment device with (ZFW) or without (FW) Zn delivery capability
settingRural households in Kisumu, western Kenya. SUBJECTS: Children aged 2-6 years.
resultsThe ZFW group had higher dietary Zn intake compared with the FW group. ZFW contributed 36 and 31 % of daily requirements for absorbable Zn in children aged 2-3 and 4-6 years, respectively, in the ZFW group. Consumption of Zn-fortified water resulted in lower prevalence of reported illness (risk ratio; 95 % CI) in the ZFW group compared with the FW group: for cold with runny nose (0·91; 0·83, 0·99; P=0·034) and abdominal pain (0·70; 0·56, 0·89; P=0·003) in the intention-to-treat analysis and for diarrhoea (0·72; 0·53, 0·96; P=0·025) in the per-protocol analysis. We did not detect an effect of treatment on plasma Zn concentration.
conclusionsDaily consumption of Zn-fortified, microbiologically treated water results in increased intake of absorbable dietary Zn and may help in preventing childhood infections in pre-school children in rural Africa.
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