Evidence map›Paper›PMID 29877048›Full record

SynthesisThoracic cancer2018

Axillary lymph node metastasis detection by magnetic resonance imaging in patients with breast cancer: A meta-analysis.

Peng Zhou, Yongqing Wei, Guoyue Chen, Lei Guo, Deyue Yan, Ying Wang

Abstract readMeta-Analysis
In one paragraph

Synthesis in Thoracic cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Deep learning-based breast MRI for predicting axillary lymph node metastasis: a systematic review and meta-analysis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Pooled it
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  10. Predictive Value ofDiagnostics (Basel, Switzerland) · 2022
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  11. Theranostic Interpolation of Genomic Instability in Breast Cancer.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peng ZhouDepartment of Radiology, Jinan Central Hospital Affiliated to Shan Dong University, Jinan, China.
Yongqing WeiDepartment of Obstetrics, Jinan Central Hospital Affiliated to Shan Dong University, Jinan, China.
Guoyue ChenDepartment of Radiology, Jinan Central Hospital Affiliated to Shan Dong University, Jinan, China.
Lei GuoDepartment of Radiology, Jinan Central Hospital Affiliated to Shan Dong University, Jinan, China.
Deyue YanDepartment of Radiology, Jinan Central Hospital Affiliated to Shan Dong University, Jinan, China.
Ying WangDepartment of Radiology, Jinan Central Hospital Affiliated to Shan Dong University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe study was conducted to evaluate the diagnostic performance of magnetic resonance imaging (MRI) for the detection of axillary lymph node metastasis in patients with breast cancer.

methodsPubMed, Medline, Web of Science, Cochrane Embase, Chinese Biomedical Literature, and China National Knowledge Infrastructure databases were searched for open published studies relevant to the use of MRI for the detection of axillary lymph node metastasis in breast cancer patients. The pooled diagnostic sensitivity, specificity, and the symmetric receiver operating characteristic (SROC) curve was calculated by combining the individual data extracted from 26 included studies.

resultsThe pooled diagnostic sensitivity and specificity of MRI to detect axillary lymph node metastasis in patients with breast cancer were 0.77 (95% confidence interval [CI] 0.75-0.80) and 0.90 (95% CI 0.89-0.91), respectively. The pooled positive and negative likelihood ratios were 7.67 (95% CI 5.09-11.53) and 0.23 (95% CI 0.17-0.32), respectively, by random effect method. The area under the SROC curve was 0.93 for MRI to detect axillary lymph node metastasis in breast cancer patients.

conclusionWith high sensitivity, specificity, and area under the curve, MRI is an effective method to differentiate metastatic axillary lymph node in breast cancer patients, which can provide useful information for surgical procedure selection.

Indexed as

AdultAgedAged, 80 and overArea Under CurveAxillaBreast NeoplasmsFemaleHumansLymphatic MetastasisMagnetic Resonance ImagingMiddle AgedROC CurveSensitivity and SpecificityYoung AdultAxillary lymph node metastasisbreast cancerdiagnosismeta-analysis

Identifiers

PMID29877048
PMCPMC6068453

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.