Evidence map›Paper›PMID 29876876›Full record

SynthesisSports medicine (Auckland, N.Z.)2018

The Effect of Acute Caffeine Ingestion on Endurance Performance: A Systematic Review and Meta-Analysis.

Kyle Southward, Kay J Rutherfurd-Markwick, Ajmol Ali

Erratum issued Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05906303 (Caffeine in the Second Stage), which is not on this map. Cited by 124 papers, 27 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 27 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05906303 phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Caffeine in the Second Stage: A Randomized Control Trial in Low-risk Nulliparous Mothers at Term

TypeinterventionalSponsorThe Reading Hospital and Medical CenterRan2023 to 2025Enrolled80ConditionsSecond Stage of LaborArmsCaffeine and Sodium Benzoate Injection, Normal Saline
3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 27 syntheses or guidelines pooled it.

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64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kyle SouthwardSchool of Sport, Exercise and Nutrition, Massey University, North Shore Mail Centre, Private Bag 102 904, Auckland, 0745, New Zealand.
Kay J Rutherfurd-MarkwickSchool of Health Sciences, Massey University, Auckland, New Zealand.
Ajmol AliSchool of Sport, Exercise and Nutrition, Massey University, North Shore Mail Centre, Private Bag 102 904, Auckland, 0745, New Zealand. a.ali@massey.ac.nz.ORCID http://orcid.org/0000-0002-6093-1435

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaffeine is a widely used ergogenic aid with most research suggesting it confers the greatest effects during endurance activities. Despite the growing body of literature around the use of caffeine as an ergogenic aid, there are few recent meta-analyses that quantitatively assess the effect of caffeine on endurance exercise.

objectivesTo summarise studies that have investigated the ergogenic effects of caffeine on endurance time-trial performance and to quantitatively analyse the results of these studies to gain a better understanding of the magnitude of the ergogenic effect of caffeine on endurance time-trial performance.

methodsA systematic review was carried out on randomised placebo-controlled studies investigating the effects of caffeine on endurance performance and a meta-analysis was conducted to determine the ergogenic effect of caffeine on endurance time-trial performance.

resultsForty-six studies met the inclusion criteria and were included in the meta-analysis. Caffeine has a small but evident effect on endurance performance when taken in moderate doses (3-6 mg/kg) as well as an overall improvement following caffeine compared to placebo in mean power output (3.03 ± 3.07%; effect size = 0.23 ± 0.15) and time-trial completion time (2.22 ± 2.59%; effect size = 0.41 ± 0.2). However, differences in responses to caffeine ingestion have been shown, with two studies reporting slower time-trial performance, while five studies reported lower mean power output during the time-trial.

conclusionCaffeine can be used effectively as an ergogenic aid when taken in moderate doses, such as during sports when a small increase in endurance performance can lead to significant differences in placements as athletes are often separated by small margins.

Indexed as

Athletic PerformanceCaffeineCentral Nervous System StimulantsCoffeeExerciseHumansPerformance-Enhancing SubstancesPhysical EnduranceSportsCaffeineCentral Nervous System StimulantsCoffeePerformance-Enhancing Substances

Identifiers

PMID29876876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.