Evidence map›Paper›PMID 29876774›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018

Rapid antigen test use for the management of group A streptococcal pharyngitis in community pharmacies.

Béatrice Demoré, Gianpiero Tebano, Julien Gravoulet, Christophe Wilcke, Eric Ruspini, Jacques Birgé, Jean-Marc Boivin, Sandrine Hénard, Annick Dieterling, Lidiana Munerol and 4 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. A Review ofPathogens (Basel, Switzerland) · 2021
    Review
  9. Review
  10. Point-of-Care Testing for Pharyngitis in the Pharmacy.Antibiotics (Basel, Switzerland) · 2020
    Article
  11. Review
  12. Review
  13. Detection of group a Streptococcus in pharyngitis by two rapid tests: comparison of the BD Veritor™ and the QuikRead go® Strep A.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Béatrice DemoréPharmacie Brabois Adultes, CHRU Nancy, Nancy, France.
Gianpiero TebanoANTIBIOLOR, CHRU Nancy, Réseau Lorrain d'Antibiologie, Nancy, France. gianpiero.tebano@gmail.com.ORCID http://orcid.org/0000-0003-1891-4823
Julien GravouletANTIBIOLOR, CHRU Nancy, Réseau Lorrain d'Antibiologie, Nancy, France.
Christophe WilckeUnion Régionale des Professionnels de Santé Pharmaciens du Grand Est, 4 rue Piroux, Nancy, France.
Eric RuspiniUnion Régionale des Professionnels de Santé Pharmaciens du Grand Est, 4 rue Piroux, Nancy, France.
Jacques BirgéANTIBIOLOR, CHRU Nancy, Réseau Lorrain d'Antibiologie, Nancy, France.
Jean-Marc BoivinANTIBIOLOR, CHRU Nancy, Réseau Lorrain d'Antibiologie, Nancy, France.
Sandrine HénardInfectious Diseases Department, Université de Lorraine, CHRU Nancy, F-54000, Nancy, France.
Annick DieterlingAgence Régionale de Santé du Grand Est. Direction de la Santé Publique, Nancy, France.
Lidiana MunerolAgence Régionale de Santé du Grand Est. Direction de la Santé Publique, Nancy, France.
Julie HussonDépartement Analyse des Données de Santé, Agence Régionale de Santé du Grand Est. Direction de la Qualité et de la Performance, Nancy, France.
Christian RabaudANTIBIOLOR, CHRU Nancy, Réseau Lorrain d'Antibiologie, Nancy, France.
Céline PulciniUniversité de Lorraine, APEMAC, F-54000, Nancy, France.
Sophie MalblancAgence Régionale de Santé du Grand Est. Direction de la Santé Publique, Nancy, France.
Agence Régionale de Santé Ile-de-France · FRUniversité de Lorraine · FRCentre d’Investigation Clinique Innovation Technologique de Nancy · FRCentre National de la Recherche Scientifique · FRInterdisciplinarité en Santé Publique Interventions et Instruments de mesure complexes – Région Est · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite group A streptococci being an infrequent cause of pharyngitis in adult outpatients, sore throat remains a common indication for antibiotic prescription. This prospective multicentre non-randomised study describes a community pharmacy-based antimicrobial stewardship intervention consisting in the implementation of rapid antigen testing (RAT) for the management of adults with sore throat. Trained pharmacists triaged patients presenting with symptoms of pharyngitis using the modified Centor score. Those at risk for streptococcal infection were tested with RAT. Patients with a positive RAT were invited to consult a physician, whereas others were offered a symptomatic treatment. All patients received educational leaflets and were asked to fill in a follow-up form 7 days later. Ninety-eight pharmacies in one French region participated, and 559 patients were included over 6 months. RAT was proposed in 367 (65.7%) cases, and it was positive in 28 (8.3%). The follow-up form was returned by 140 (38.5%) participants. Of these, 10/10 patients with positive RAT further consulted a physician and were prescribed an antibiotic treatment, whereas 96.5% (110/114) of patients with negative results and not having any other reason to seek for doctor's advice did not consult. All participants found the intervention useful. Pharmacists spent 6-15 min to perform the intervention, and 98.6% (73/74) of pharmacists giving a feedback declared to be ready to implement this intervention in daily practice, if endorsed and reimbursed. Our results suggest that a pharmacy-based programme for the management of sore throat is feasible and could increase adherence to guidelines.

Indexed as

Anti-Bacterial AgentsFemaleFollow-Up StudiesFranceGuideline AdherenceHumansImmunologic TestsMalePharmaciesPharmacistsPharyngitisProspective StudiesReferral and ConsultationStreptococcal InfectionsStreptococcus pyogenesAnti-Bacterial AgentsAntibioticsAntibiotic stewardshipCommunity pharmacyPharyngitisPoint-of-care testingStreptococcus pyogenes

Identifiers

PMID29876774
OpenAlexW2807264006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.