Evidence map›Paper›PMID 29876610›Full record

ReviewDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2018

[Possibilities and limitations of molecular pathology in dermatohistology].

V Schacht, U Lehmann, T Reineke-Plaass, F Länger, B Auber, S Morlot, H-H Kreipe

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

V SchachtKlinik für Dermatologie, Allergologie und Venerologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. schacht.vivien@mh-hannover.de.
U LehmannInstitut für Pathologie, Medizinische Hochschule Hannover, Hannover, Deutschland.
T Reineke-PlaassInstitut für Pathologie, Medizinische Hochschule Hannover, Hannover, Deutschland.
F LängerInstitut für Pathologie, Medizinische Hochschule Hannover, Hannover, Deutschland.
B AuberInstitut für Humangenetik, Medizinische Hochschule Hannover, Hannover, Deutschland.
S MorlotInstitut für Humangenetik, Medizinische Hochschule Hannover, Hannover, Deutschland.
H-H KreipeInstitut für Pathologie, Medizinische Hochschule Hannover, Hannover, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant tumours, infections caused by microorganisms or genodermatoses are diagnosed with additional help of molecular pathology methods. Polymerase chain reaction (PCR), sequencing and in situ hybridisations play an important role. It remains to be seen if methods such as "liquid biopsies" or "single cell genomics" can be developed as routine diagnostics. High technical efforts, high costs and no possibility for resistency testing is accompanied by fast verification, high sensitivity and high specificity. Overall, molecular pathology results have to be combined with the clinical picture, histology or immunohistochemistry and culturing results to achieve a correct diagnosis for the patient.

Indexed as

Pathology, MolecularBiomarkers, TumorGenetic TestingHistological TechniquesHistologyHumansImmunohistochemistryNeoplasmsPolymerase Chain ReactionSkinSkin DiseasesBiomarkers, TumorFluorescence in situ hybridizationMonoclonal expansionMutationPolymerase chain reactionSequencing

Identifiers

PMID29876610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.