ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2018
Optimal cross selection for long-term genetic gain in two-part programs with rapid recurrent genomic selection.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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Who cites it
90 citing papers in PubMed.
- Balancing gain and diversity: Optimal contribution selection for sustainable genetic improvement in sugarcane.The plant genome · 2026Review
- The effect of selection on allele frequencies and diversity in wheat (Triticum aestivum).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genetic dissection of cold tolerance across developmental stages in sorghum reveals stage-specific haplotypes and potential trade-offs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Prioritization of deleterious mutations informs genomic prediction and increases the rate of gain in common bean (Phaseolus vulgaris L.), a simulation study.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Bridging tradition and innovation: a review of computer simulations in plant breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Optimizing progeny size and number of crosses under genomic selection: insights into additive and epistatic contributions to long-term genetic gain.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Optimization of family sizes in sets of crosses with a greedy allocation strategy based on automatic differentiation.Frontiers in plant science · 2026Article
- Derivation of prediction error variance for non-genotyped individuals in genomic selection.Frontiers in genetics · 2026Article
- Accelerated breeding modernization: a global blueprint for driving genetic gains, climate resilience, and food security in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- A Novel Conservation Genomic Strategy: Selection for the Probability of Offspring Heterozygosity.Animals : an open access journal from MDPI · 2025Article
- Optimization of recurrent rapid cycle breeding in maize for sustained long-term genetic improvement via stochastic simulations.G3 (Bethesda, Md.) · 2025Article
- Genomic selection of maize test-cross hybrids leveraged by marker sampling.The plant genome · 2025Article
- Rapid cycling genomic selection in maize landraces.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- SimpleMating: R-package for prediction and optimization of breeding crosses using genomic selection.The plant genome · 2025Article
- Within-family genomic selection in strawberry: Optimization of marker density, trial design, and training set composition.The plant genome · 2025Article
- Optimal implementation of genomic selection in clone breeding programs exemplified in potato: II. Effect of selection strategy and cross-selection method on long-term genetic gain.The plant genome · 2025Article
- Micronutrient Biofortification in Wheat: QTLs, Candidate Genes and Molecular Mechanism.International journal of molecular sciences · 2025Review
- Is there an advantage of using genomic information to estimate gametic variances and improve recurrent selection in animal populations?Genetics, selection, evolution : GSE · 2025Article
- Tester selection for combining ability estimation of storage root yield and sweetpotato virus disease in sweetpotato breeding.Scientific reports · 2025Article
- Genomic selection shows improved expected genetic gain over phenotypic selection of agronomic traits in allotetraploid white clover.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
30 more citing papers are in PubMed but not listed here.
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3 authors.
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Abstract
Key message Optimal cross selection increases long-term genetic gain of two-part programs with rapid recurrent genomic selection. It achieves this by optimising efficiency of converting genetic diversity into genetic gain through reducing the loss of genetic diversity and reducing the drop of genomic prediction accuracy with rapid cycling. This study evaluates optimal cross selection to balance selection and maintenance of genetic diversity in two-part plant breeding programs with rapid recurrent genomic selection. The two-part program reorganises a conventional breeding program into a population improvement component with recurrent genomic selection to increase the mean value of germplasm and a product development component with standard methods to develop new lines. Rapid recurrent genomic selection has a large potential, but is challenging due to genotyping costs or genetic drift. Here we simulate a wheat breeding program for 20 years and compare optimal cross selection against truncation selection in the population improvement component with one to six cycles per year. With truncation selection we crossed a small or a large number of parents. With optimal cross selection we jointly optimised selection, maintenance of genetic diversity, and cross allocation with AlphaMate program. The results show that the two-part program with optimal cross selection delivered the largest genetic gain that increased with the increasing number of cycles. With four cycles per year optimal cross selection had 78% (15%) higher long-term genetic gain than truncation selection with a small (large) number of parents. Higher genetic gain was achieved through higher efficiency of converting genetic diversity into genetic gain; optimal cross selection quadrupled (doubled) efficiency of truncation selection with a small (large) number of parents. Optimal cross selection also reduced the drop of genomic selection accuracy due to the drift between training and prediction populations. In conclusion optimal cross selection enables optimal management and exploitation of population improvement germplasm in two-part programs.
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