Evidence map›Paper›PMID 29876281›Full record

ArticleNeuroImage. Clinical2018

Postmortem diffusion MRI of the entire human spinal cord at microscopic resolution.

Evan Calabrese, Syed M Adil, Gary Cofer, Christian S Perone, Julien Cohen-Adad, Shivanand P Lad, G Allan Johnson

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Evan CalabreseDepartment of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA; Center for In Vivo Microscopy, Duke University Medical Center, Durham, NC, USA. Electronic address: edc15@duke.edu.
Syed M AdilCenter for In Vivo Microscopy, Duke University Medical Center, Durham, NC, USA; Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
Gary CoferCenter for In Vivo Microscopy, Duke University Medical Center, Durham, NC, USA.
Christian S PeroneNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.
Julien Cohen-AdadNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.
Shivanand P LadDepartment of Neurosurgery, Duke University Medical Center, Durham, NC, USA.
G Allan JohnsonCenter for In Vivo Microscopy, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · USPolytechnique Montréal · CAUniversity of California System · US

Funding

INTEGRATED CENTER FOR IN VIVO MICROSCOPYP41EB015897 · NIBIB · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2012 to 2017
$7.4M
Agilent Direct Drive 9.4T MRS/MRI ConsoleS10OD010683 · OD · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2012 to 2012
$597k
NIBIB NIH HHS P41 EB015897NIH HHS S10 OD010683
6 · The paper itself

Abstract

The human spinal cord is a central nervous system structure that plays an important role in normal motor and sensory function, and can be affected by many debilitating neurologic diseases. Due to its clinical importance, the spinal cord is frequently the subject of imaging research. Common methods for visualizing spinal cord anatomy and pathology include histology and magnetic resonance imaging (MRI), both of which have unique benefits and drawbacks. Postmortem microscopic resolution MRI of fixed specimens, sometimes referred to as magnetic resonance microscopy (MRM), combines many of the benefits inherent to both techniques. However, the elongated shape of the human spinal cord, along with hardware and scan time limitations, have restricted previous microscopic resolution MRI studies (both

Indexed as

Magnetic Resonance ImagingCross-Sectional StudiesDiffusion Magnetic Resonance ImagingGray MatterHumansImage Processing, Computer-AssistedMaleNeuroimagingSpinal CordSpinal Cord DiseasesWhite MatterGray matterHumanMagnetic resonance microscopySpinal cordTractography

Identifiers

PMID29876281
PMCPMC5988447
OpenAlexW2795150941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.