ArticleNeuroImage. Clinical2018
Impaired conscious access and abnormal attentional amplification in schizophrenia.
Article in NeuroImage. Clinical, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Ketamine disrupts consciousness in healthy participants in relation with psychotic-like symptoms.bioRxiv : the preprint server for biology · 2025Article
- The glare illusion in individuals with schizophrenia.Schizophrenia research. Cognition · 2025Article
- Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia.Neuroscience of consciousness · 2025Article
- Neural signatures of visual awareness independent of postperceptual processing.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Dorsal attention network activity during perceptual organization is distinct in schizophrenia and predictive of cognitive disorganization.The European journal of neuroscience · 2023Article
- Perceptual Functioning.Current topics in behavioral neurosciences · 2023Article
- Preserved Unconscious Processing in Schizophrenia: The Case of Motivation.Schizophrenia bulletin · 2022Article
- Delayed access to conscious processing in multiple sclerosis: Reduced cortical activation and impaired structural connectivity.Human brain mapping · 2021Article
- The neural correlates of the visual consciousness in schizophrenia: an fMRI study.European archives of psychiatry and clinical neuroscience · 2021Article
- Disruption of Conscious Access in Psychosis Is Associated with Altered Structural Brain Connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Review
- Opportunities and challenges for a maturing science of consciousness.Nature human behaviour · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous research suggests that the conscious perception of a masked stimulus is impaired in schizophrenia, while unconscious bottom-up processing of the same stimulus, as assessed by subliminal priming, can be preserved. Here, we test this postulated dissociation between intact bottom-up and impaired top-down processing and evaluate its brain mechanisms using high-density recordings of event-related potentials. Sixteen patients with schizophrenia and sixteen controls were exposed to peripheral digits with various degrees of visibility, under conditions of either focused attention or distraction by another task. In the distraction condition, the brain activity evoked by masked digits was drastically reduced in both groups, but early bottom-up visual activation could still be detected and did not differ between patients and controls. By contrast, under focused top-down attention, a major impairment was observed: in patients, contrary to controls, the late non-linear ignition associated with the P3 component was reduced. Interestingly, the patients showed an essentially normal attentional amplification of the P1 and N2 components. These results suggest that some but not all top-down attentional amplification processes are impaired in schizophrenia, while bottom-up processing seems to be preserved.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.