ArticleOncotarget2018
Meta-analysis of homocysteine-related factors on the risk of colorectal cancer.
Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Folate and global health umbrella review series, part 2: syntheses on cancers.Journal of global health · 2026Pooled it
- Pooled it
- A systematic review and meta-analysis of homocysteine concentrations in chronic obstructive pulmonary disease.Clinical and experimental medicine · 2023Pooled it
- Homocysteine levels and cancer risk in hypertensive adults across MTHFR C677T genotypes.Scientific reports · 2026Article
- Decoding metabolic dysfunction in cancer: foundations for early detection and personalized therapeutics.Frontiers in endocrinology · 2025Review
- The association between non- and pro-healthy diet indices and the risk of colorectal cancer: a case-control study.BMC gastroenterology · 2024Article
- Elevated serum homocysteine levels associated with poor recurrence-free and overall survival in patients with colorectal cancer.Scientific reports · 2024Article
- Review
- Association of Serum Homocysteine with Cardiovascular and All-Cause Mortality in Adults with Diabetes: A Prospective Cohort Study.Oxidative medicine and cellular longevity · 2022Article
- Metabolic Evidence Rather Than Amounts of Red or Processed Meat as a Risk on Korean Colorectal Cancer.Metabolites · 2021Article
- Cysteine and homocysteine as biomarker of various diseases.Food science & nutrition · 2020Review
- Blockade of the trans-sulfuration pathway in acute pancreatitis due to nitration of cystathionine β-synthase.Redox biology · 2020Article
- Cys34 Adductomics Links Colorectal Cancer with the Gut Microbiota and Redox Biology.Cancer research · 2019Article
- Association of Polymorphisms in Genes Involved in One-Carbon Metabolism withInternational journal of molecular sciences · 2019Article
- Gene-Metabolite Interaction in the One Carbon Metabolism Pathway: Predictors of Colorectal Cancer in Multi-Ethnic Families.Journal of personalized medicine · 2018Article
- Predictors of the Healthy Eating Index and Glycemic Index in Multi-Ethnic Colorectal Cancer Families.Nutrients · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The major objective of this meta-analysis was to examine the association between homocysteine and related measurements with the risk of colorectal cancer (CRC) and adenomatous polyps (AP). Many studies presented an association between
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.