Evidence map›Paper›PMID 29875795›Full record

ArticleFrontiers in genetics2018

Gene-Expression Analysis Identifies IGFBP2 Dysregulation in Dental Pulp Cells From Human Cleidocranial Dysplasia.

Stephen L Greene, Olga Mamaeva, David K Crossman, Changming Lu, Mary MacDougall

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Amyloid-mediated remineralization for tooth hypoplasia of cleidocranial dysplasia.Frontiers in cellular and infection microbiology · 2023
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Stephen L GreeneDepartment of Pediatric Dentistry, School of Dentistry, The University of Alabama at Birmingham, Birmingham, AL, United States.
Olga MamaevaInstitute of Oral Health Research, School of Dentistry, The University of Alabama at Birmingham, Birmingham, AL, United States.
David K CrossmanDepartment of Genetics, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, United States.
Changming LuInstitute of Oral Health Research, School of Dentistry, The University of Alabama at Birmingham, Birmingham, AL, United States.
Mary MacDougallFaculty of Dentistry, University of British Columbia, Vancouver, BC, Canada.
University of Alabama at Birmingham · USUniversity of British Columbia · CA

Funding

Dental Academic Research Training Program (DART)T90DE022736 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Amjad Javed · 2012 to 2026
$6.7M
NIDCR NIH HHS T90 DE022736
6 · The paper itself

Abstract

Cleidocranial dysplasia (CCD) is an autosomal dominant disorder affecting osteoblast differentiation, chondrocyte maturation, skeletal morphogenesis, and tooth formation. Dental phenotype in CCD include over-retained primary teeth, failed eruption of permanent teeth, and supernumerary teeth. The underlying mechanism is unclear. We previously reported one CCD patient with allelic

Indexed as

cleidocranial dysplasiadentinogenesisIGFIGFBP2RUNX2

Identifiers

PMID29875795
PMCPMC5974155
OpenAlexW2799505110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.