ArticleFrontiers in pharmacology2018
Anti-hyperplasia Effects of Total Saponins From Phytolaccae Radix in Rats With Mammary Gland Hyperplasia via Inhibition of Proliferation and Induction of Apoptosis.
Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Exploratory Clinical Trial of Honghua Xiaoyao Pills for the Treatment of Liver Depression and Haemostasis-Type Hyperplasia of Mammary Glands: A Single-Centre, Single-Arm Study.The breast journal · 2026Trial
- [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Modified Estrogen-Progesterone Induction Method of Mammary Gland Hyperplasia in Rats.Bulletin of experimental biology and medicine · 2023Article
- Commentary: Anti-hyperplasia effects of total saponins from phytolaccae radix in rats with mammary gland hyperplasia via inhibition of proliferation and induction of apoptosis.Frontiers in pharmacology · 2023Article
- Effects ofFrontiers in endocrinology · 2022Article
- Therapeutic effects and mechanism of ferulic acid and icariin in mammary gland hyperplasia model rats via regulation of the ERK pathway.Annals of translational medicine · 2021Article
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Authors and funding
13 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Mammary gland hyperplasia (MGH) is a pathological condition that affects the majority of women at the child-bearing stage. The hormone and endocrinal therapy are typically used to treat MGH. Nevertheless, there are still some certain side effects accompanied with the benefits, which negatively affect the life quality of patients. Therefore, plant-derived agents that are effective against MGH development and with fewer side effects should be developed. The aim of this study was to investigate the protective effects and underlying mechanism of total saponins of Phytolaccae (TSP) against MGH
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