Evidence map›Paper›PMID 29875623›Full record

ArticleFrontiers in neuroscience2018

Reduction of Movement in Neurological Diseases: Effects on Neural Stem Cells Characteristics.

Raffaella Adami, Jessica Pagano, Michela Colombo, Natalia Platonova, Deborah Recchia, Raffaella Chiaramonte, Roberto Bottinelli, Monica Canepari, Daniele Bottai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Raffaella AdamiDepartment of Health Science, University of Milan, Milan, Italy.
Jessica PaganoDepartment of Health Science, University of Milan, Milan, Italy.
Michela ColomboDepartment of Health Science, University of Milan, Milan, Italy.
Natalia PlatonovaDepartment of Health Science, University of Milan, Milan, Italy.
Deborah RecchiaDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Raffaella ChiaramonteDepartment of Health Science, University of Milan, Milan, Italy.
Roberto BottinelliDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Monica CanepariDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Daniele BottaiDepartment of Health Science, University of Milan, Milan, Italy.
University of Milan · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both astronauts and patients affected by chronic movement-limiting pathologies face impairment in muscle and/or brain performance. Increased patient survival expectations and the expected longer stays in space by astronauts may result in prolonged motor deprivation and consequent pathological effects. Severe movement limitation can influence not only the motor and metabolic systems but also the nervous system, altering neurogenesis and the interaction between motoneurons and muscle cells. Little information is yet available about the effect of prolonged muscle disuse on neural stem cells characteristics. Our

Indexed as

astronautsCdk5RAP1hindlimb unloadingmetabolismmotor inactivityneural stem cellsneurodegenerative diseasesneurogenesis

Identifiers

PMID29875623
PMCPMC5974544
OpenAlexW2800750075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.