Evidence map›Paper›PMID 29875588›Full record

ArticleTzu chi medical journal

High serum leptin level is associated with peripheral artery disease in adult peritoneal dialysis patients.

Yu-Hsien Lai, Chih-Hsien Wang, Jen-Pi Tsai, Jia-Sian Hou, Chung-Jen Lee, Bang-Gee Hsu

Open access · diamondAbstract read
In one paragraph

Article in Tzu chi medical journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu-Hsien LaiDepartment of Nephrology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Chih-Hsien WangDepartment of Nephrology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Jen-Pi TsaiDepartment of Nephrology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
Jia-Sian HouDepartment of Nursing, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Chung-Jen LeeDepartment of Nursing, Tzu Chi University of Science and Technology, Hualien, Taiwan.
Bang-Gee HsuDepartment of Nephrology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Buddhist Tzu Chi General Hospital · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePeripheral artery disease (PAD) is associated with systemic atherosclerosis and indicates an increased risk of mortality in peritoneal dialysis (PD) patients. A high leptin level accelerates atherosclerosis in apoE-deficient mice. The purpose of this study was to examine the association of serum leptin level and PAD in adult PD patients. MATERIALS AND

methodsThe clinical characteristics of sixty PD patients recruited from June 2015 to October 2016 were obtained. Serum leptin concentrations were determined. Ankle-brachial index (ABI) values were measured and those with a left or right ABI <0.9 were defined as the low ABI group.

resultsTwenty of these 60 PD patients (33.3%) had diabetes mellitus and 32 patients (53.3%) had hypertension. Thirteen PD patients (21.7%) were in the low ABI group. Higher serum leptin (

conclusionHigher serum leptin and CRP levels correlated positively with the diagnosis of PAD in PD patients.

Indexed as

C-reactive proteinLeptinPeripheral artery diseasePeritoneal dialysis

Identifiers

PMID29875588
PMCPMC5968748
OpenAlexW2792557558

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.