Evidence map›Paper›PMID 29875400›Full record

ArticleMucosal immunology2018

Microbial dysbiosis associated with impaired intestinal Na

Christy A Harrison, Daniel Laubitz, Christina L Ohland, Monica T Midura-Kiela, Karuna Patil, David G Besselsen, Deepa R Jamwal, Christian Jobin, Fayez K Ghishan, Pawel R Kiela

Open access · bronzeAbstract read
In one paragraph

Article in Mucosal immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
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  14. Review
  15. Review
  16. New functions and roles of the NaPflugers Archiv : European journal of physiology · 2024
    Review
  17. Claudin-2 upregulation enhances intestinal permeability, immune activation, dysbiosis, and mortality in sepsis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
  19. Dietary Polyphenols SupportAntioxidants (Basel, Switzerland) · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Christy A HarrisonDepartment of Pediatrics, Steele Children's Research Center, Tucson, AZ, USA.
Daniel LaubitzDepartment of Pediatrics, Steele Children's Research Center, Tucson, AZ, USA.
Christina L OhlandUniversity Animal Care, University of Arizona, Tucson, AZ, USA.
Monica T Midura-KielaDepartment of Pediatrics, Steele Children's Research Center, Tucson, AZ, USA.
Karuna PatilUniversity Animal Care, University of Arizona, Tucson, AZ, USA.
David G BesselsenUniversity Animal Care, University of Arizona, Tucson, AZ, USA.
Deepa R JamwalDepartment of Pediatrics, Steele Children's Research Center, Tucson, AZ, USA.
Christian JobinDivision of Gastroenterology, Department of Medicine, University of Florida College of Medicine, Gainesville, FL, USA.
Fayez K GhishanDepartment of Pediatrics, Steele Children's Research Center, Tucson, AZ, USA.
Pawel R KielaDepartment of Pediatrics, Steele Children's Research Center, Tucson, AZ, USA. pkiela@peds.arizona.edu.
University of Arizona · USChildren's Center · USUniversity of Florida · US

Funding

DEVELOPMENT OF INTESTINAL ION TRANSPORTR01DK041274 · NIDDK · VANDERBILT UNIVERSITY · PI GHISHAN, FAYEZ KHALAF, KIELA, PAWEL R · 1988 to 2016
$5.5M
The role of klebsiella pneumonia-derived colibactin in colitis-associated colon cancerR01DK073338 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOBIN, CHRISTIAN · 2007 to 2023
$5.4M
NIDDK NIH HHS R01 DK041274NIDDK NIH HHS R01 DK073338
6 · The paper itself

Abstract

Intestinal epithelial Na

Indexed as

AnimalsBacillotaBacteroidaceaeColitisDysbiosisEpithelial CellsFemaleGastrointestinal MicrobiomeGerm-Free LifeHydrogen-Ion ConcentrationImmunityInflammationInflammatory Bowel DiseasesInterleukin-10Intestinal MucosaMaleInterleukin-10Sodium-Hydrogen Exchanger 3Sodium-Hydrogen Exchangers

Identifiers

PMID29875400
PMCPMC6162102
OpenAlexW2805580066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.