Evidence map›Paper›PMID 29875260›Full record

ArticleThe Journal of cell biology2018

The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion.

Tina L Sing, Minnie P Hung, Shinsuke Ohnuki, Godai Suzuki, Bryan-Joseph San Luis, Melainia McClain, Jay R Unruh, Zulin Yu, Jiongwen Ou, Jesse Marshall-Sheppard and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Genome-Scale Screening ofJournal of fungi (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 4 countries.

Tina L SingDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-2166-969X
Minnie P HungDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-4724-5171
Shinsuke OhnukiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Chiba, Japan.ORCID 0000-0001-6254-081X
Godai SuzukiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Chiba, Japan.
Bryan-Joseph San LuisDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.
Melainia McClainStowers Institute for Medical Research, Kansas City, MO.ORCID 0000-0002-8947-9841
Jay R UnruhStowers Institute for Medical Research, Kansas City, MO.ORCID 0000-0003-3077-4990
Zulin YuStowers Institute for Medical Research, Kansas City, MO.
Jiongwen OuDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Jesse Marshall-SheppardDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-0664-5673
Won-Ki HuhDepartment of Biological Sciences, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0002-9091-6594
Michael CostanzoDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-7906-2604
Charles BooneDonnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada.
Yoshikazu OhyaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Chiba, Japan.
Sue L JaspersenStowers Institute for Medical Research, Kansas City, MO.ORCID 0000-0001-8312-7063
Grant W BrownDepartment of Biochemistry, University of Toronto, Toronto, Ontario, Canada grant.brown@utoronto.ca.ORCID 0000-0002-9002-5003
University of Toronto · CAStowers Institute for Medical Research · USThe University of Tokyo · JPSeoul National University · KR

Funding

Mapping the reference genetic network of a eukaryotic cellR01HG005853 · NHGRI · UNIVERSITY OF TORONTO · PI ANDREWS, BRENDA JEAN, BOONE, CHARLES · 2010 to 2025
$7.6M
Assembly and Regulation of Yeast Spindle PolesR01GM121443 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI GERTON, JENNIFER L · 2017 to 2020
$1.3M
NHGRI NIH HHS R01 HG005853NIGMS NIH HHS R01 GM121443
6 · The paper itself

Abstract

Ploidy is tightly regulated in eukaryotic cells and is critical for cell function and survival. Cells coordinate multiple pathways to ensure replicated DNA is segregated accurately to prevent abnormal changes in chromosome number. In this study, we characterize an unanticipated role for the

Indexed as

Cell Cycle ProteinsChromosomal Proteins, Non-HistoneChromosome SegregationCytoskeletal ProteinsDNA-Binding ProteinsNuclear EnvelopeNuclear Pore Complex ProteinsNuclear ProteinsPloidiesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSpindle ApparatusSpindle Pole BodiesTranscription FactorsCell Cycle ProteinsChromosomal Proteins, Non-HistoneCytoskeletal ProteinsDNA-Binding ProteinsNBP1 protein, S cerevisiaeNDC1 protein, S cerevisiaeNuclear Pore Complex ProteinsNuclear ProteinsRSC complex, S cerevisiaeSaccharomyces cerevisiae ProteinsSWI-SNF-B chromatin-remodeling complexTranscription Factors

Identifiers

PMID29875260
PMCPMC6028538
OpenAlexW2806417234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.