Evidence map›Paper›PMID 29875195›Full record

ReviewJournal of clinical microbiology2018

Laboratory Diagnosis of Neurocysticercosis (Taenia solium).

Hector H Garcia, Seth E O'Neal, John Noh, Sukwan Handali, Cysticercosis Working Group in Peru

Abstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hector H GarciaCysticercosis Unit, Instituto Nacional de Ciencias Neurologicas, Lima, Peru hgarcia@jhsph.edu.
Seth E O'NealSchool of Public Health, Oregon Health & Science University-Portland State University, Portland, Oregon, USA.
John NohDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Sukwan HandaliDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Cysticercosis Working Group in Peru

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurocysticercosis accounts for approximately 30% of all epilepsy cases in most developing countries. The immunodiagnosis of cysticercosis is complex and strongly influenced by the course of infection, the disease burden, the cyst location, and the immune response of the host. The main approach to immunodiagnosis should thus be to evaluate whether the serological results are consistent with the diagnosis suggested by imaging. Antibody detection is performed using lentil lectin-purified parasite antigens in an enzyme-linked immunoelectrotransfer blot format, while antigen detection uses a monoclonal antibody-based enzyme-linked immunosorbent assay (ELISA). Promising new assay configurations have been developed for the detection of both antibody and antigen, including assays based on synthetic or recombinant antigens that may reduce costs and improve assay reproducibility and multiplex bead-based assays that may provide simultaneous quantitative results for several target antigens or antibodies.

Indexed as

ImmunoassayImmunologic TestsAnimalsAntibodies, HelminthAntigens, HelminthCysticercusHumansNeurocysticercosisReproducibility of ResultsTaenia soliumAntibodies, HelminthAntigens, HelminthantibodyantigencysticercosisEITBELISAneurocysticercosisPeruTaenia soliumWestern blot

Identifiers

PMID29875195
PMCPMC6113464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.