Evidence map›Paper›PMID 29875193›Full record

ArticleJournal of clinical microbiology2018

Performance of Vitek MS v3.0 for Identification of Mycobacterium Species from Patient Samples by Use of Automated Liquid Medium Systems.

Eric Miller, Christopher Cantrell, Melodie Beard, Andrew Derylak, N Esther Babady, Tracy McMillen, Edwin Miranda, Barbara Body, Yi-Wei Tang, Ravikiran Vasireddy and 8 more

Open access · bronzeAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Diagnostic performance of MALDI-TOF MS for non-tuberculous mycobacteria: A systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Eric MillerbioMérieux Inc., R&D Microbiology, Durham, North Carolina, USA.
Christopher CantrellbioMérieux Inc., R&D Microbiology, Durham, North Carolina, USA.
Melodie BeardDepartment of Esoteric Microbiology, LabCorp of America, Burlington, North Carolina, USA.
Andrew DerylakDepartment of Esoteric Microbiology, LabCorp of America, Burlington, North Carolina, USA.
N Esther BabadyDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0003-4399-1249
Tracy McMillenDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Edwin MirandaDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Barbara BodyDepartment of Esoteric Microbiology, LabCorp of America, Burlington, North Carolina, USA.
Yi-Wei TangDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0003-4888-6771
Ravikiran VasireddyMycobacteria/Nocardia Laboratory, The University of Texas Health Science Center at Tyler, Tyler, Texas, USA.
Sruthi VasireddyMycobacteria/Nocardia Laboratory, The University of Texas Health Science Center at Tyler, Tyler, Texas, USA.
Terry SmithMycobacteria/Nocardia Laboratory, The University of Texas Health Science Center at Tyler, Tyler, Texas, USA.
Elena IakhiaevaMycobacteria/Nocardia Laboratory, The University of Texas Health Science Center at Tyler, Tyler, Texas, USA.
Richard J WallaceMycobacteria/Nocardia Laboratory, The University of Texas Health Science Center at Tyler, Tyler, Texas, USA.
Barbara A Brown-ElliottMycobacteria/Nocardia Laboratory, The University of Texas Health Science Center at Tyler, Tyler, Texas, USA.
Erik MorenobioMérieux Inc., R&D Microbiology, Durham, North Carolina, USA.
Heather TottybioMérieux Inc., R&D Microbiology, Durham, North Carolina, USA.
Parampal DeolbioMérieux Inc., R&D Microbiology, Durham, North Carolina, USA Parampal.Deol@biomerieux.com.
The University of Texas Health Science Center at Tyler · USbioMérieux (United States) · USMemorial Sloan Kettering Cancer Center · USLabCorp (United States) · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

The accuracy and robustness of the Vitek MS v3.0 matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (MS) system was evaluated by identifying mycobacteria from automated liquid-medium systems using patient samples. This is the first report to demonstrate that proteins within the liquid medium, its supplements, and decontamination reagents for nonsterile patient samples do not generate misidentification or false-positive results by use of the Vitek MS v3.0 system. Prior to testing with patient samples, a seeded-culture study was conducted to challenge the accuracy of the Vitek MS system at identifying mycobacteria from liquid medium by mimicking a clinical workflow. Seventy-seven

Indexed as

Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationBacteriological TechniquesCulture MediaDiagnostic Tests, RoutineHumansMycobacteriumMycobacterium Infections, NontuberculousSputumCulture Medialiquid mediaMALDI-TOFmycobacteria

Identifiers

PMID29875193
PMCPMC6062784
OpenAlexW2807522778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.